{"id":"W2163560007","doi":"10.1128/jvi.79.5.3107-3116.2005","title":"Estradiol Regulates Susceptibility following Primary Exposure to Genital Herpes Simplex Virus Type 2, while Progesterone Induces Inflammation","year":2005,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Ontario HIV Treatment Network","keywords":"Herpes simplex virus; Biology; Viral shedding; Inflammation; Virus; Hormone; Vagina; Immunology; Internal medicine; Endocrinology; Medicine; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009582669,0.0002257323,0.0002163868,0.0001745788,0.0001232402,0.0003315207,0.00007765176,0.0001669768,0.0009365817],"category_scores_gemma":[0.0001962816,0.00008560341,0.0001353055,0.00008162768,0.0001961667,0.0001843849,0.000173633,0.0002745942,0.0001852936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001232974,"about_ca_system_score_gemma":0.0001223076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002037764,"about_ca_topic_score_gemma":0.0003855737,"domain_scores_codex":[0.9998902,0.00002529382,0.000006894044,0.00002159393,0.00002082677,0.00003512469],"domain_scores_gemma":[0.9998566,0.00001692115,0.00005295379,0.00001256816,0.00001775704,0.00004325872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001059906,0.00006510183,0.007874631,0.00006324446,0.00001512855,0.00026052,0.00009288207,0.00004260346,0.9836948,0.0001213098,0.0000989148,0.006610868],"study_design_scores_gemma":[0.0000814488,0.003734457,0.2521798,0.00004721634,0.0001542823,0.001802742,0.0005718945,0.000498717,0.7285764,0.0005191225,0.01180748,0.000026418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930887,0.004856605,0.0004821749,0.0001141626,0.00004556153,0.00001677653,0.0001565081,0.00002095691,0.001218554],"genre_scores_gemma":[0.9940193,0.003835358,0.0002893546,0.0000477971,0.00003286638,0.00001711532,0.0001166757,0.00000699234,0.001634516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009365817,"threshold_uncertainty_score":0.003133118,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02258486491505132,"score_gpt":0.2914526573889627,"score_spread":0.2688677924739113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}