{"id":"W2163609332","doi":"10.1111/j.1747-0285.2007.00518.x","title":"Hydrophobic Interactions in Complexes of Antimicrobial Peptides with Bacterial Polysaccharides","year":2007,"lang":"en","type":"article","venue":"Chemical Biology & Drug Design","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; McMaster University; University of Toronto","funders":"","keywords":"Glycan; Chemistry; Peptide; Biofilm; Polysaccharide; Antimicrobial peptides; Pseudomonas aeruginosa; Antimicrobial; Cationic polymerization; Antibiotics; Hydrophobic effect; Biochemistry; Biophysics; Combinatorial chemistry; Bacteria; Glycoprotein; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001714616,0.0002315131,0.000183909,0.00008315936,0.0001749652,0.0002098313,0.0001467981,0.0002505938,0.0006933583],"category_scores_gemma":[0.0002493483,0.0001418415,0.000166958,0.0000815582,0.0001853452,0.0002605288,0.0002236485,0.0002818282,0.0001609446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002263424,"about_ca_system_score_gemma":0.00009418163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003838686,"about_ca_topic_score_gemma":0.0004016066,"domain_scores_codex":[0.9998145,0.00004964387,0.00000783375,0.00002681649,0.00005485944,0.00004641584],"domain_scores_gemma":[0.9998431,0.00005706547,0.00004646736,0.000008547294,0.00001915783,0.00002552354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001208961,0.00002446664,0.0002627373,0.00003225168,0.00001021052,0.00005054347,0.00003055855,0.000132079,0.9986281,0.00004518209,0.0000252722,0.0006375811],"study_design_scores_gemma":[0.00001696576,0.000337636,0.006745724,0.0000071948,0.00001328658,0.0001882663,0.00003965315,0.0016402,0.9903024,0.00005123758,0.0006482114,0.000009179684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988511,0.0003220826,0.0004311313,0.00002132948,0.000003433735,0.000005001619,0.00001990316,0.000004667488,0.0003413406],"genre_scores_gemma":[0.9988507,0.0002112553,0.0004152176,0.00003175508,0.0000036646,0.000008279651,0.00006006037,0.000004387939,0.000414561],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006933583,"threshold_uncertainty_score":0.002319515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01710102317564629,"score_gpt":0.2493428599173475,"score_spread":0.2322418367417012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}