{"id":"W2163717729","doi":"10.1038/mp.2013.160","title":"DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan","year":2014,"lang":"en","type":"letter","venue":"Molecular Psychiatry","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"National Institute of Mental Health; Medical Research Council","keywords":"DISC1; Mental illness; Schizophrenia (object-oriented programming); Psychiatry; Risk factor; Psychology; Medicine; Clinical psychology; Genetics; Mental health; Biology; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001453385,0.000462845,0.0003113329,0.0001640994,0.0001965161,0.00007129334,0.0002141606,0.0007638786,0.0001229487],"category_scores_gemma":[0.0001054845,0.0004385667,0.0002508587,0.0001007226,0.000084658,0.000002905394,0.0001113207,0.0003531828,0.00007444161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002474526,"about_ca_system_score_gemma":0.000115759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001540602,"about_ca_topic_score_gemma":0.00001890035,"domain_scores_codex":[0.9978766,0.0002807376,0.0003647331,0.0008816865,0.0002137537,0.0003824935],"domain_scores_gemma":[0.9988623,0.00002026946,0.000229943,0.0006712,0.00005528191,0.000161064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00447155,0.00008187276,0.0006719203,0.0001864126,0.0007556046,0.00004536908,0.0001452992,0.00002521996,0.1808001,0.0000409495,0.8066851,0.006090618],"study_design_scores_gemma":[0.002446959,0.0009696682,0.004342391,0.0000889927,0.0001823279,0.0001649808,0.00002289144,0.00003229261,0.008857124,0.0004043046,0.9816111,0.0008769426],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8334793,0.002053161,0.005991236,0.1528258,0.002755587,0.001777737,0.0005937876,0.00008016806,0.000443189],"genre_scores_gemma":[0.4795401,0.0002757012,0.01907374,0.4470637,0.004155581,0.000632394,0.003063506,0.00103169,0.04516356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3539392,"threshold_uncertainty_score":0.9998066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003697168090356986,"score_gpt":0.2272402643217921,"score_spread":0.2235430962314351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}