{"id":"W2163737705","doi":"10.1002/humu.22637","title":"Instability of Trinucleotidic Repeats During Chromatin Remodeling in Spermatids","year":2014,"lang":"en","type":"article","venue":"Human Mutation","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Biology; Chromatin remodeling; Chromatin; Trinucleotide repeat expansion; Genome instability; Transgene; Genetics; Anticipation (artificial intelligence); Cell biology; Gene; DNA; DNA damage; Allele","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003312609,0.00007166147,0.0001021482,0.00005428373,0.00003421659,0.00000620176,0.00009785834,0.00006409122,0.00001569156],"category_scores_gemma":[0.0001546123,0.00007939766,0.00003916518,0.00005498562,0.00002386435,0.000005701113,0.00005338817,0.00004300918,0.000003342111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002204026,"about_ca_system_score_gemma":0.00001300877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002553909,"about_ca_topic_score_gemma":0.00006132476,"domain_scores_codex":[0.9992452,0.00008937684,0.0002780745,0.0001935724,0.00009317489,0.0001006265],"domain_scores_gemma":[0.9994996,0.000005517418,0.00009916208,0.000333471,0.00004029588,0.00002198363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001556802,0.00003058098,0.001375207,0.00006674741,0.000003151515,6.217813e-7,0.0002852404,0.0007635123,0.9962144,0.0001554028,0.000002545363,0.00108706],"study_design_scores_gemma":[0.000681676,0.0001179441,0.06063166,0.00003718589,0.000004509733,0.000005747355,0.0001199856,0.003234749,0.9334872,0.001563782,0.00001728131,0.00009821398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978135,0.00002157234,0.00105788,0.00001045421,0.00002905653,0.0001284378,0.000001289591,0.00001479862,0.0009229988],"genre_scores_gemma":[0.9979948,0.000002540534,0.001842458,0.00001256116,0.00004085475,0.000006988571,0.00004755404,0.00001177028,0.00004046778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06272709,"threshold_uncertainty_score":0.3237742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00999595994756911,"score_gpt":0.2506455526542393,"score_spread":0.2406495927066702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}