{"id":"W2163751473","doi":"10.1093/hmg/ddi218","title":"Interindividual variability and parent of origin DNA methylation differences at specific human Alu elements","year":2005,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Center for Research Resources; National Institute of Environmental Health Sciences","keywords":"Biology; Methylation; DNA methylation; Alu element; Genetics; CpG site; Epigenetics; Differentially methylated regions; Epigenetics of physical exercise; RNA-Directed DNA Methylation; Genomic imprinting; Gene; Human genome; Genome; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003957826,0.0002258957,0.0002187334,0.00006877621,0.0001399112,0.00003280667,0.0001967053,0.0001559324,0.0001060224],"category_scores_gemma":[0.00002341144,0.0002344212,0.00008630505,0.00006484473,0.0001516055,0.000003796608,0.0002717685,0.00007578847,0.00000357343],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003430818,"about_ca_system_score_gemma":0.00001928037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004974395,"about_ca_topic_score_gemma":0.00003907612,"domain_scores_codex":[0.998304,0.000181783,0.0005181552,0.0004828353,0.0002704858,0.0002427146],"domain_scores_gemma":[0.9990775,0.00001235483,0.0002221059,0.0004762656,0.0001074513,0.0001043292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001282515,0.00009104352,0.05969428,0.00001992728,0.00005317626,7.354557e-7,0.00009698517,0.0001017076,0.9343953,0.0003902632,0.0000344056,0.005109392],"study_design_scores_gemma":[0.0005600849,0.0004164221,0.2399762,0.00001162912,0.00004392432,0.000001240925,0.00001914506,0.00007740781,0.7484919,0.0009785107,0.009158696,0.0002647666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992685,0.001896048,0.00426912,0.00002358897,0.00006425929,0.000261756,0.00002887817,0.000009317441,0.0007620537],"genre_scores_gemma":[0.9960522,0.0004136643,0.002948815,0.00002704768,0.0001393184,0.00001546519,0.0002777455,0.0000281231,0.00009759137],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1859033,"threshold_uncertainty_score":0.9559421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03725213266431832,"score_gpt":0.3084275516410396,"score_spread":0.2711754189767213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}