{"id":"W2163787552","doi":"10.1084/jem.20072681","title":"The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?","year":2008,"lang":"en","type":"letter","venue":"The Journal of Experimental Medicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":396,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"HIV vaccine; Virology; AIDS Vaccines; Human immunodeficiency virus (HIV); Medicine; Immunology; Vaccine trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01144736,0.001001919,0.00207814,0.0004757339,0.001908005,0.002927013,0.002399414,0.03127405,0.004835613],"category_scores_gemma":[0.02745689,0.000436742,0.001381408,0.0005314367,0.00348239,0.004552153,0.001025898,0.0249804,0.00514673],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003142906,"about_ca_system_score_gemma":0.001811284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008300178,"about_ca_topic_score_gemma":0.001873619,"domain_scores_codex":[0.9940281,0.003087727,0.0005520126,0.0005767096,0.001363932,0.0003916562],"domain_scores_gemma":[0.9845256,0.01065593,0.0007816979,0.0005143939,0.001806102,0.001716297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004620015,0.0001324216,0.001199558,0.0003064186,0.00006544474,0.004568573,0.0001674366,0.00007677873,0.0006185324,0.005720254,0.9366915,0.04999115],"study_design_scores_gemma":[0.001106029,0.001059105,0.002358905,0.0007636721,0.0001383266,0.0103887,0.0007088289,0.0008527539,0.00130159,0.01758746,0.9636204,0.0001142805],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0007477393,0.004480768,0.0001582163,0.9774168,0.01589531,0.00001480327,0.00002730482,0.00002610316,0.001233024],"genre_scores_gemma":[0.007188829,0.003576173,0.000489391,0.9381279,0.04770283,0.00004590204,0.00002767204,0.00002189932,0.002819429],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03127405,"threshold_uncertainty_score":0.06054014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0277286224728915,"score_gpt":0.3081849565549724,"score_spread":0.2804563340820809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}