{"id":"W2163808572","doi":"10.1186/1741-7007-9-31","title":"PKC isoforms interact with and phosphorylate DNMT1","year":2011,"lang":"en","type":"article","venue":"BMC Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Protein kinase C; DNMT1; Phosphorylation; Biology; Gene isoform; DNA methylation; Methylation; HEK 293 cells; Cell biology; Molecular biology; Biochemistry; Gene expression; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001596724,0.0005042756,0.0001952146,0.0002616821,0.0002933452,0.0003226936,0.0002115025,0.0002496523,0.004462245],"category_scores_gemma":[0.0002864471,0.0001800268,0.0004515428,0.0002285213,0.0001306862,0.0002892767,0.0003188864,0.0005648828,0.001400955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006378438,"about_ca_system_score_gemma":0.0002943526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0010637,"about_ca_topic_score_gemma":0.0009365803,"domain_scores_codex":[0.9998266,0.0000165832,0.00001330738,0.00004822466,0.00003633522,0.00005893111],"domain_scores_gemma":[0.999801,0.00002255054,0.00007517864,0.00002339618,0.00003169611,0.00004619152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000545144,0.0000673395,0.003446936,0.0001525165,0.00002787106,0.00007983437,0.00002832989,0.0001047726,0.9909593,0.0001217862,0.0001815578,0.004284495],"study_design_scores_gemma":[0.00005254163,0.0001806035,0.05014364,0.00002639154,0.00006440801,0.0005660788,0.00005898429,0.001084932,0.9420561,0.0001338644,0.005623031,0.00000931533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887717,0.006107866,0.002080501,0.0002432277,0.00008857789,0.00002945814,0.0005143724,0.00005472975,0.002109581],"genre_scores_gemma":[0.9865302,0.003965554,0.001581238,0.00008328007,0.0000515097,0.00003595031,0.001137236,0.00002809487,0.006586975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004462245,"threshold_uncertainty_score":0.01492769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02536083270846087,"score_gpt":0.2515788777317013,"score_spread":0.2262180450232404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}