{"id":"W2163825189","doi":"10.1002/bit.22590","title":"Bioreactor expansion of human neural precursor cells in serum‐free media retains neurogenic potential","year":2009,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of Calgary","funders":"","keywords":"Bioreactor; Precursor cell; Basic fibroblast growth factor; Cell culture; Stem cell; Transplantation; Cell biology; Biology; In vitro; Chemistry; Neuroscience; Growth factor; Biochemistry; Medicine; Internal medicine; Genetics; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001190725,0.0001724716,0.0001917488,0.000251393,0.00003595547,0.000008180282,0.0003190798,0.0004769799,0.000003818966],"category_scores_gemma":[0.00004281364,0.0001668027,0.000059704,0.0001996492,0.0001283152,0.000006479216,0.0001903612,0.0002374514,0.000001314012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009944585,"about_ca_system_score_gemma":0.00001783106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000719966,"about_ca_topic_score_gemma":0.00001480977,"domain_scores_codex":[0.9989235,0.00002724746,0.000237448,0.0003578062,0.000112123,0.0003418436],"domain_scores_gemma":[0.9994508,0.000007178665,0.00005225575,0.0004019213,0.00002452345,0.00006333667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000355045,0.00003966689,0.0002908041,0.0000211148,0.00001540058,0.00002313549,0.00001506493,0.00008842014,0.9967198,0.00006393986,0.00003232456,0.002654876],"study_design_scores_gemma":[0.0005702178,0.0004692373,0.008341654,0.00001721945,0.00001053286,0.00002983514,0.00002323132,0.001025018,0.9891509,0.00003033645,0.0001734753,0.0001583835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979006,0.001068511,0.000243288,0.000428256,0.00009583602,0.000171188,0.00002836718,0.00004348954,0.0000204491],"genre_scores_gemma":[0.9990515,0.0005089552,0.0002947544,0.00002408803,0.00005155742,0.000003871269,0.00002621624,0.0000148564,0.0000241634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00805085,"threshold_uncertainty_score":0.6802017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008387224285229493,"score_gpt":0.2258968298328209,"score_spread":0.2175096055475914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}