{"id":"W2163828524","doi":"10.1117/1.jbo.17.5.056008","title":"Spatial frequency domain tomography of protoporphyrin IX fluorescence in preclinical glioma models","year":2012,"lang":"en","type":"article","venue":"Journal of Biomedical Optics","topic":"Photoacoustic and Ultrasonic Imaging","field":"Engineering","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Air Force Office of Scientific Research; National Institute of Biomedical Imaging and Bioengineering; National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institutes of Health; University of Toronto; Fondation pour la Recherche Médicale; Dartmouth College; Arnold and Mabel Beckman Foundation","keywords":"Protoporphyrin IX; Spheroid; In vivo; Glioma; Fluorescence; Spatial frequency; Tomography; Optics; Nuclear magnetic resonance; Attenuation coefficient; Materials science; Glioblastoma; Scattering; Biomedical engineering; Contrast (vision); Nuclear medicine; Chemistry; Physics; Medicine; Biology; In vitro; Cancer research","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002621173,0.0004876677,0.0002202665,0.0005411073,0.00008690684,0.0001531779,0.0003269506,0.0003312546,0.0005585201],"category_scores_gemma":[0.00022883,0.0002164825,0.0001373086,0.0002425596,0.0002262505,0.0002885495,0.0001589336,0.0004929977,0.0001587677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003304078,"about_ca_system_score_gemma":0.0002918981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001690618,"about_ca_topic_score_gemma":0.001553572,"domain_scores_codex":[0.9999254,0.00001560991,0.000003151147,0.00001364812,0.0000271101,0.00001523678],"domain_scores_gemma":[0.9999135,0.00001932716,0.00002614312,0.00001298971,0.00001508439,0.00001301076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001348653,0.00003677512,0.00009977436,0.00002440913,0.000003867503,0.00005107741,0.00001185421,0.001012842,0.99677,0.00008106842,0.000041423,0.00173201],"study_design_scores_gemma":[0.00003734231,0.0008878311,0.002336924,0.000005351358,0.00002508197,0.0006572962,0.00003369844,0.01284703,0.9822903,0.0001018519,0.0007696232,0.000007728528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.963157,0.001124931,0.03361244,0.0001262802,0.00001270845,0.00008760798,0.0003649323,0.0003181807,0.001195824],"genre_scores_gemma":[0.9719219,0.001110156,0.02479407,0.00004080671,0.000005658352,0.0001314969,0.0003919697,0.00004214564,0.001561859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001690618,"threshold_uncertainty_score":0.003361583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01701288165186789,"score_gpt":0.2623805267339652,"score_spread":0.2453676450820974,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}