{"id":"W2163927795","doi":"10.2174/1389450023347713","title":"Purine Signaling and Potential New Therapeutic Approach: Possible Outcomes of NTPDase Inhibition","year":2002,"lang":"en","type":"review","venue":"Current Drug Targets","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; University of Missouri; National Institutes of Health; American Diabetes Association","keywords":"Purine; Computational biology; Chemistry; Computer science; Biology; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001448125,0.0004540438,0.0009276909,0.0001295319,0.00007208709,0.00003175613,0.0001769223,0.0002162105,0.00005384201],"category_scores_gemma":[0.00002223268,0.000363334,0.0004355221,0.0001183579,0.00006595512,0.000007106217,0.000165675,0.0002469379,0.000006919746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001271761,"about_ca_system_score_gemma":0.0001080706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006740059,"about_ca_topic_score_gemma":1.729311e-7,"domain_scores_codex":[0.9982925,0.0001141627,0.0005743874,0.0005295749,0.0001958886,0.0002934604],"domain_scores_gemma":[0.9990838,0.00001792108,0.0003879183,0.0003136817,0.00005546787,0.0001411879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002210256,0.0004615226,0.0001071999,0.01212042,0.000666447,0.00001249533,0.0001245342,0.00006316356,0.0008273476,0.00008752979,0.01353896,0.9719683],"study_design_scores_gemma":[0.0007844268,0.00009054056,0.000009570908,0.002026663,0.001002503,0.00006311911,0.00002108675,0.00004599485,0.001505104,0.0001186902,0.9935732,0.0007591419],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007632188,0.9966569,0.001646729,0.000016416,0.0003093114,0.0004164824,0.00006721593,0.0000158668,0.0001078947],"genre_scores_gemma":[0.004256998,0.9928795,0.0003572056,0.00001837655,0.0006494072,0.00002637835,0.000931196,0.0000560936,0.0008248544],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9800342,"threshold_uncertainty_score":0.9998819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04190373149415329,"score_gpt":0.3047436508335212,"score_spread":0.2628399193393679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}