{"id":"W2163987144","doi":"10.1002/mabi.201100051","title":"The Role of Dimension in Multivalent Binding Events: Structure–Activity Relationship of Dendritic Polyglycerol Sulfate Binding to <scp>L</scp>‐Selectin in Correlation with Size and Surface Charge Density","year":2011,"lang":"en","type":"article","venue":"Macromolecular Bioscience","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Deutsche Forschungsgemeinschaft","keywords":"Chemistry; Selectin; Biophysics; E-selectin; Cell adhesion; In vitro; Ligand (biochemistry); Adhesion; Stereochemistry; Biochemistry; Cell; Receptor; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007999779,0.0001576072,0.0002546095,0.0002925154,0.0001435952,0.00001334,0.0001617324,0.00008892218,0.000006195758],"category_scores_gemma":[0.002022882,0.000120237,0.00003476472,0.001439824,0.0002013645,0.00009927394,0.000155382,0.0003178381,0.000003738711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001409428,"about_ca_system_score_gemma":0.0001135942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005788263,"about_ca_topic_score_gemma":0.0002612956,"domain_scores_codex":[0.9979899,0.0002557238,0.0003132618,0.0004284352,0.0006098023,0.000402883],"domain_scores_gemma":[0.9986998,0.000556306,0.0001629812,0.0003064766,0.0001309164,0.0001434533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001019702,0.00006687604,0.4019328,0.00002272748,0.000003700866,0.00001738753,0.0006304972,0.00002900014,0.5970011,0.00004410804,3.244158e-7,0.0001495046],"study_design_scores_gemma":[0.0005052576,0.0002082574,0.4601208,0.0001424156,0.000008633151,0.00002312974,0.0002422148,0.001784889,0.5368766,0.00004664141,0.000001451558,0.00003975293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998674,0.00009845095,0.0003068759,0.00004610675,0.00003592158,0.0007345496,0.00000752476,0.000009956882,0.00008661983],"genre_scores_gemma":[0.9985127,0.00001804251,0.001333628,0.000009466124,0.000002453716,0.000005533411,0.00000213136,0.0000166816,0.00009933035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06012451,"threshold_uncertainty_score":0.4903122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01574348669167149,"score_gpt":0.259372276229458,"score_spread":0.2436287895377865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}