{"id":"W2163987144","doi":"10.1002/mabi.201100051","title":"The Role of Dimension in Multivalent Binding Events: Structure–Activity Relationship of Dendritic Polyglycerol Sulfate Binding to <scp>L</scp>‐Selectin in Correlation with Size and Surface Charge Density","year":2011,"lang":"en","type":"article","venue":"Macromolecular Bioscience","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Deutsche Forschungsgemeinschaft","keywords":"Chemistry; Selectin; Biophysics; E-selectin; Cell adhesion; In vitro; Ligand (biochemistry); Adhesion; Stereochemistry; Biochemistry; Cell; Receptor; Organic chemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001287952,0.0002051782,0.0001194447,0.0001314993,0.00005664418,0.0002584878,0.0001529208,0.0001803748,0.0008921258],"category_scores_gemma":[0.0002823437,0.0001006318,0.0001138824,0.0001177509,0.0001604456,0.0001643645,0.0001145302,0.0002027566,0.0001754093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002635985,"about_ca_system_score_gemma":0.0001167881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006244236,"about_ca_topic_score_gemma":0.0004795223,"domain_scores_codex":[0.9999086,0.00001503653,0.00000479332,0.0000155158,0.00002739472,0.00002871383],"domain_scores_gemma":[0.9997727,0.00009025545,0.00006023672,0.000009587099,0.00002616935,0.0000410883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001228074,0.00002592959,0.0006026892,0.00001738579,0.000005835022,0.00001884562,0.00001513083,0.0002074216,0.997917,0.00008093293,0.00002710926,0.0009589782],"study_design_scores_gemma":[0.000008713574,0.0002309524,0.01514695,0.000003223091,0.0000122632,0.0000682142,0.00002359115,0.005170673,0.9787397,0.00005958169,0.0005263592,0.000009816247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985564,0.000374707,0.000585382,0.00002050131,0.000002852628,0.000004976295,0.00005829795,0.000009980074,0.0003869032],"genre_scores_gemma":[0.9989212,0.0002311581,0.0003644838,0.00002971475,0.000002845229,0.000007109313,0.00009467078,0.000003235094,0.0003456057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008921258,"threshold_uncertainty_score":0.002984464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01574348669167149,"score_gpt":0.259372276229458,"score_spread":0.2436287895377865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}