{"id":"W2164043360","doi":"10.1139/o04-034","title":"Histone modifications and DNA double-strand break repair","year":2004,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"DNA repair; Homologous recombination; Histone; Homology directed repair; Biology; Cell biology; Double strand; Histone H2A; Ku80; Replication protein A; DNA repair protein XRCC4; DNA damage; DNA; Genetics; Nucleotide excision repair; DNA-binding protein; Gene; Transcription factor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001777037,0.0005614234,0.0008294983,0.00005416681,0.0001422841,0.00002447221,0.0002648258,0.001376274,0.00002519606],"category_scores_gemma":[0.00002321168,0.0005108175,0.0003313218,0.00009223269,0.0003860937,0.000002726338,0.0002420961,0.0002644077,0.00001137567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004698353,"about_ca_system_score_gemma":0.000333296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001640892,"about_ca_topic_score_gemma":0.000002341172,"domain_scores_codex":[0.9978266,0.00006751308,0.0004920473,0.001160184,0.00006630646,0.000387292],"domain_scores_gemma":[0.998681,0.00002286431,0.0002695351,0.0007524415,0.00005097333,0.0002231503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001551275,0.0003840108,0.000006409853,0.03048184,0.0006202915,0.00003003643,0.00004011027,7.650282e-7,0.7749374,0.001133531,0.001361541,0.190849],"study_design_scores_gemma":[0.000674371,0.0001561067,4.391418e-7,0.0005338485,0.000373054,0.0002200395,0.00001414426,8.873276e-7,0.1191381,0.00008567193,0.8782341,0.0005691869],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003648479,0.9908543,0.00005157387,0.00001504454,0.00014225,0.0004250365,0.0002146614,0.00006614543,0.004582535],"genre_scores_gemma":[0.004298805,0.9889959,0.0005858834,0.00003490167,0.0002655198,0.0001442279,0.001741827,0.00005686056,0.003876075],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8768726,"threshold_uncertainty_score":0.9999201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02080041837977431,"score_gpt":0.2891693707308582,"score_spread":0.2683689523510839,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}