{"id":"W2164098001","doi":"10.1093/hmg/9.13.1927","title":"Copper-dependent trafficking of Wilson disease mutant ATP7B proteins","year":2000,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Trace Elements in Health","field":"Nursing","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Medical Research Council; Medical Research Council Canada; University of Alberta","keywords":"Biology; Endoplasmic reticulum; Golgi apparatus; Ceruloplasmin; Mutant; Menkes disease; Yeast; Transport protein; Saccharomyces cerevisiae; ATP7A; Cell biology; Genetics; Gene; Biochemistry; Copper; Transporter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001710345,0.0004350365,0.0002486292,0.0002282363,0.0002537828,0.0003915949,0.000372523,0.0003170925,0.0006979855],"category_scores_gemma":[0.0001668299,0.0001808133,0.0002153889,0.0002236756,0.0002757435,0.0002033463,0.0003886409,0.0004061522,0.0004297991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004581061,"about_ca_system_score_gemma":0.0001465715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001289776,"about_ca_topic_score_gemma":0.001674156,"domain_scores_codex":[0.9998424,0.00002747414,0.00002476046,0.00002975372,0.00005650914,0.00001905479],"domain_scores_gemma":[0.9998667,0.00002198909,0.00003116411,0.00002113541,0.00002251596,0.00003648892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003808126,0.00001163576,0.0002868983,0.00002185655,0.000003650963,0.00008921901,0.00001512209,0.0000509364,0.9990447,0.00007331253,0.00001827192,0.000346241],"study_design_scores_gemma":[0.00001612819,0.0000856943,0.004207612,0.000005176428,0.000008038838,0.0008327068,0.00005003712,0.002285025,0.9908648,0.00006922035,0.001567311,0.000008220805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964461,0.0003185624,0.00234545,0.00005351168,0.00001011421,0.00001715177,0.000392587,0.00004100246,0.0003756175],"genre_scores_gemma":[0.9906299,0.0003630221,0.006192944,0.00003648517,0.00000325567,0.00003517495,0.001300854,0.00006344971,0.001374897],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001289776,"threshold_uncertainty_score":0.003323793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01929988309058624,"score_gpt":0.2990999067237484,"score_spread":0.2798000236331622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}