{"id":"W2164128280","doi":"10.4049/jimmunol.169.7.3883","title":"The Human Antimicrobial Peptide LL-37 Is a Multifunctional Modulator of Innate Immune Responses","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":708,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"","keywords":"Chemokine; Innate immune system; Biology; CXCL2; Immune system; CCR2; CCL18; Macrophage inflammatory protein; Chemokine receptor; Beta defensin; Immunology; Proinflammatory cytokine; Antimicrobial peptides; Monocyte; Macrophage; Cell biology; Cytokine; Inflammation; Microbiology; Antimicrobial; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001479452,0.0005990098,0.0003507058,0.0002632903,0.0001853429,0.0004561956,0.0001163725,0.000200845,0.001004501],"category_scores_gemma":[0.0001734849,0.0001075777,0.0002186074,0.0001650049,0.0003887087,0.0001808076,0.0003259149,0.0003091785,0.0004223818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004379719,"about_ca_system_score_gemma":0.0002847122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003397388,"about_ca_topic_score_gemma":0.000229165,"domain_scores_codex":[0.9998533,0.00003097819,0.00001242349,0.00002900418,0.00003701705,0.00003728902],"domain_scores_gemma":[0.999903,0.00001586515,0.00003281653,0.000007214922,0.00001116061,0.00002995446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001612627,0.00001277677,0.0007698683,0.0001056765,0.000006594421,0.0002315639,0.00002237915,0.0001001487,0.9905384,0.0001190938,0.0001016379,0.007830596],"study_design_scores_gemma":[0.00002972209,0.001006925,0.02481135,0.000073355,0.00006325038,0.002703231,0.0001221803,0.0007610744,0.9451581,0.0005367484,0.02470775,0.00002624724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9226359,0.06435184,0.007778246,0.0004941634,0.0001416962,0.00005837984,0.0005143645,0.0002297804,0.003795703],"genre_scores_gemma":[0.9849101,0.009761061,0.002542783,0.0001624427,0.00007651534,0.00003139357,0.000346823,0.00001540125,0.002153571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001004501,"threshold_uncertainty_score":0.003360331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0181604868024256,"score_gpt":0.2354542489628004,"score_spread":0.2172937621603748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}