{"id":"W2164147551","doi":"10.1200/jco.2005.10.126","title":"Phenotypic Heterogeneity in Multiple Myeloma Families","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Creighton University; National Cancer Institute; U.S. Department of Health and Human Services; National Institutes of Health; University of Nebraska Medical Center; Nebraska Department of Health and Human Services","keywords":"Medicine; Proband; Multiple myeloma; Family history; Family aggregation; Population; Observational study; Family studies; Genetics; Pathology; Internal medicine; Mutation; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002054128,0.0001217301,0.00115948,0.0002111251,0.00003022205,0.000006177026,0.0001481867,0.0002813825,0.0001518589],"category_scores_gemma":[0.005500299,0.00008276199,0.0004043932,0.0001421359,0.0001778634,0.0001271406,0.0000553776,0.0008781989,0.0001243875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002426941,"about_ca_system_score_gemma":0.0009032097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003915903,"about_ca_topic_score_gemma":0.0008629403,"domain_scores_codex":[0.9968824,0.0003951895,0.001846438,0.000169893,0.0003833955,0.0003226569],"domain_scores_gemma":[0.9966114,0.001866433,0.0005920321,0.000189308,0.0002422898,0.0004985512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003671603,0.001938744,0.5523033,0.00001041195,0.0001618911,0.000756286,0.00004053257,0.00002168792,0.0002023822,0.00001262328,0.0005059955,0.4403746],"study_design_scores_gemma":[0.01674488,0.004848434,0.9152743,0.00004711501,0.0000594505,0.000255211,0.00005892609,0.0007088716,0.0005242976,0.00005962076,0.06135667,0.00006227833],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910233,0.0006282911,0.00005742033,0.004764169,0.0003326611,0.0001891381,0.000002590641,0.000008184571,0.002994263],"genre_scores_gemma":[0.9872047,0.0007783928,0.009527984,0.001155422,0.001124356,0.000004252199,0.000002479337,0.0000123631,0.000190049],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4403123,"threshold_uncertainty_score":0.6584769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1828600453116601,"score_gpt":0.4861984207155332,"score_spread":0.3033383754038731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}