{"id":"W2164154861","doi":"10.1002/9780470015902.a0023273","title":"<scp>CRISPR</scp> / <scp>Cas</scp> System and Resistance to Bacteriophage Infection","year":2011,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"CRISPR; Extrachromosomal DNA; Biology; Trans-activating crRNA; CRISPR interference; Plasmid; Genetics; DNA; Bacteriophage; Cas9; Horizontal gene transfer; RNA; Gene; Computational biology; Genome; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001998686,0.0003228007,0.0002802382,0.0005097701,0.0002635452,0.0003955488,0.0003961393,0.0004989252,0.004077741],"category_scores_gemma":[0.0002331003,0.0001014886,0.000263977,0.000202914,0.0003994855,0.0002132042,0.0003629999,0.0008033147,0.001003232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006607673,"about_ca_system_score_gemma":0.0002631342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007094784,"about_ca_topic_score_gemma":0.0003374112,"domain_scores_codex":[0.9997974,0.00002735249,0.00001666815,0.00004722528,0.00007297372,0.00003845856],"domain_scores_gemma":[0.9998327,0.00003296843,0.00005814356,0.00001805462,0.0000213917,0.00003673993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001704669,0.00006059108,0.0006141544,0.0001525775,0.00002145875,0.0003489417,0.0000278,0.0002920995,0.9833499,0.004207177,0.001433968,0.0093209],"study_design_scores_gemma":[0.00007274016,0.0006335761,0.02323075,0.00004471948,0.00005424863,0.004134657,0.00006301046,0.007374008,0.9182584,0.00419667,0.04188002,0.000057163],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9020944,0.01119234,0.04073279,0.001341223,0.0003523434,0.0002621847,0.002243619,0.001920989,0.03986014],"genre_scores_gemma":[0.9796001,0.0009023082,0.003960464,0.0001631698,0.00003352721,0.00008568286,0.0009983184,0.00004907526,0.01420729],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.004077741,"threshold_uncertainty_score":0.01364136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007943730804677692,"score_gpt":0.2576960905615082,"score_spread":0.2497523597568305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}