{"id":"W2164202885","doi":"10.1128/mcb.21.16.5332-5345.2001","title":"Hic-5-Reduced Cell Spreading on Fibronectin: Competitive Effects between Paxillin and Hic-5 through Interaction with Focal Adhesion Kinase","year":2001,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; McGill University; Institute of Medical Science, University of Tokyo; Takeda Science Foundation","keywords":"Paxillin; Focal adhesion; PTK2; RHOA; Cell biology; Integrin; Vinculin; Tyrosine phosphorylation; CDC42; Biology; Proto-oncogene tyrosine-protein kinase Src; Cell adhesion; Signal transduction; Fibronectin; Actin cytoskeleton; Cytoskeleton; Cell; Biochemistry; Protein kinase C; Extracellular matrix; Mitogen-activated protein kinase kinase","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001419258,0.0005039532,0.0002930449,0.0002177488,0.0001564189,0.0002482452,0.0003209151,0.0003210577,0.001477981],"category_scores_gemma":[0.00008542882,0.0001606535,0.0003216888,0.0001245523,0.0002112113,0.0001601588,0.0002006275,0.0007156992,0.0001940059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004104068,"about_ca_system_score_gemma":0.0002834874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001864241,"about_ca_topic_score_gemma":0.002823001,"domain_scores_codex":[0.999818,0.00002444623,0.00001484555,0.00003102255,0.00004685444,0.00006476991],"domain_scores_gemma":[0.9999268,0.00001180572,0.00001292916,0.000007649711,0.000007920061,0.00003303857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006830556,0.00003184775,0.00005251367,0.00002975623,0.000006823208,0.00001830842,0.000004138643,0.00002409843,0.9993231,0.00006082631,0.00002065753,0.0003597279],"study_design_scores_gemma":[0.0000192737,0.0003449564,0.003453292,0.000004106842,0.00002108105,0.000065545,0.00001156431,0.0005531573,0.994792,0.00000913026,0.0007226052,0.000003138147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948815,0.00186964,0.001372539,0.00008140392,0.00003199214,0.00003476886,0.0002404528,0.00004490735,0.00144271],"genre_scores_gemma":[0.995917,0.0005277001,0.0009759711,0.000074528,0.000008775128,0.00004529682,0.0005262579,0.000008087111,0.001916446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001864241,"threshold_uncertainty_score":0.004944384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01631542602313798,"score_gpt":0.2889670388333228,"score_spread":0.2726516128101848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}