{"id":"W2164202885","doi":"10.1128/mcb.21.16.5332-5345.2001","title":"Hic-5-Reduced Cell Spreading on Fibronectin: Competitive Effects between Paxillin and Hic-5 through Interaction with Focal Adhesion Kinase","year":2001,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; McGill University; Institute of Medical Science, University of Tokyo; Takeda Science Foundation","keywords":"Paxillin; Focal adhesion; PTK2; RHOA; Cell biology; Integrin; Vinculin; Tyrosine phosphorylation; CDC42; Biology; Proto-oncogene tyrosine-protein kinase Src; Cell adhesion; Signal transduction; Fibronectin; Actin cytoskeleton; Cytoskeleton; Cell; Biochemistry; Protein kinase C; Extracellular matrix; Mitogen-activated protein kinase kinase","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001717655,0.000301134,0.0004716838,0.0001632867,0.0001391486,0.00002991149,0.0000754251,0.0002580503,0.00005127941],"category_scores_gemma":[0.00006958299,0.0002362434,0.00007979778,0.0001912479,0.0002086978,0.00004833776,0.0001120254,0.0005005936,0.00003710998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006866165,"about_ca_system_score_gemma":0.00003945365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001102414,"about_ca_topic_score_gemma":0.000005664907,"domain_scores_codex":[0.9981332,0.0003227829,0.0002302397,0.0006639071,0.000211584,0.0004383143],"domain_scores_gemma":[0.9990281,0.000277301,0.00008231804,0.0002985102,0.000077505,0.0002363046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008339791,0.0001546519,0.009346673,0.0001636105,0.00007728598,0.001029947,0.0001552274,0.000004316403,0.9799528,0.0003633084,0.00002170257,0.007896477],"study_design_scores_gemma":[0.002593993,0.005152868,0.00422005,0.0002463416,0.00013008,0.000182485,0.0002162229,0.0001700442,0.9825416,0.0001730268,0.004094917,0.0002784009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872197,0.001016918,0.00705926,0.0005040606,0.00007261388,0.0006260491,0.00000429294,0.00004781273,0.003449322],"genre_scores_gemma":[0.9981495,0.0002257303,0.0007049307,0.0003278221,0.0001039959,0.00002641781,0.0001611164,0.00004591729,0.0002545798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01092982,"threshold_uncertainty_score":0.9633726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01631542602313798,"score_gpt":0.2889670388333228,"score_spread":0.2726516128101848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}