{"id":"W2164217339","doi":"10.1093/toxsci/kft122","title":"Embryonic Catalase Protects Against Ethanol-Initiated DNA Oxidation and Teratogenesis in Acatalasemic and Transgenic Human Catalase–Expressing Mice","year":2013,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Prenatal Substance Exposure Effects","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Catalase; Offspring; Reactive oxygen species; Fetus; Chemistry; Internal medicine; Endocrinology; DNA damage; Superoxide dismutase; Transgene; Embryo; Andrology; Biochemistry; Oxidative stress; Biology; Medicine; Pregnancy; DNA; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000245816,0.0004463441,0.000324937,0.0005950967,0.0001473244,0.0003164037,0.0003020272,0.0004602675,0.001747997],"category_scores_gemma":[0.0002448792,0.0003421158,0.0002998647,0.0002163859,0.0003284487,0.0002129472,0.0002084748,0.0008436964,0.0004342087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000286841,"about_ca_system_score_gemma":0.0002923757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008699301,"about_ca_topic_score_gemma":0.0009460926,"domain_scores_codex":[0.9997175,0.00003768156,0.00004081679,0.00008657618,0.00007150546,0.00004594493],"domain_scores_gemma":[0.9995471,0.00004211893,0.0001961884,0.00005802503,0.00004197858,0.0001147164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002276602,0.00005997776,0.0001843218,0.00001642913,0.000007692454,0.00004623791,0.0000154668,0.00002746996,0.9984791,0.00006017095,0.00002987813,0.0008454837],"study_design_scores_gemma":[0.00007982692,0.0009602206,0.006633077,0.00001350094,0.00003912592,0.0004755963,0.00003659033,0.0008269449,0.9892023,0.00006911976,0.001654085,0.000009476802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931779,0.000892918,0.003846353,0.0001490007,0.00003856887,0.00005444895,0.0007398277,0.0002395098,0.0008614986],"genre_scores_gemma":[0.9887312,0.001015731,0.003383126,0.00008610954,0.00001729711,0.0001235382,0.001198184,0.00009350357,0.005351226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001747997,"threshold_uncertainty_score":0.005847633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04182172204719518,"score_gpt":0.2980743745022754,"score_spread":0.2562526524550802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}