{"id":"W2164243186","doi":"10.1158/1078-0432.ccr-05-2019","title":"Enhanced Killing of Primary Ovarian Cancer by Retargeting Autologous Cytokine-Induced Killer Cells with Bispecific Antibodies: A Preclinical Study","year":2006,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of California, Irvine; U.S. Public Health Service; University of Alberta","keywords":"Cytokine-induced killer cell; Ovarian cancer; NKG2D; Antibody; Cancer research; Cytotoxic T cell; Immunotherapy; Medicine; CD8; Antigen; Cancer; Cancer cell; Immunology; CD3; Immune system; Biology; Internal medicine; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004704883,0.0008093736,0.0008443262,0.0003847123,0.0001449826,0.0004303749,0.0004751484,0.0004593821,0.001313242],"category_scores_gemma":[0.0002394516,0.0001920527,0.0004533471,0.0002049985,0.0003275578,0.0003341269,0.0002054912,0.001086426,0.0003206983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004704608,"about_ca_system_score_gemma":0.0004318017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007171346,"about_ca_topic_score_gemma":0.0008181799,"domain_scores_codex":[0.9997523,0.00004732079,0.00001046828,0.0000404163,0.00004962275,0.00009991039],"domain_scores_gemma":[0.9998622,0.00002822936,0.00002640633,0.0000171255,0.0000201323,0.00004577615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001437243,0.003626035,0.0003466326,0.0002984563,0.00003939163,0.0001363162,0.000102266,0.0007931066,0.9807444,0.0001390118,0.0003768867,0.01196025],"study_design_scores_gemma":[0.001276725,0.05666289,0.003565513,0.00002446077,0.0001430239,0.0006489285,0.00006384031,0.00261722,0.9303038,0.0000757256,0.004606224,0.00001162687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920793,0.002538259,0.003020341,0.0001459685,0.00007344365,0.0004257173,0.0003191787,0.0001471826,0.001250516],"genre_scores_gemma":[0.9918662,0.002788744,0.002100979,0.0001029908,0.00004904322,0.0003592414,0.0006685758,0.0000318381,0.002032398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001313242,"threshold_uncertainty_score":0.00439322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1024976616993215,"score_gpt":0.4192407169054804,"score_spread":0.316743055206159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}