{"id":"W2164319622","doi":"10.4049/jimmunol.175.7.4797","title":"Adoptive Transfer of Tumor-Reactive Melan-A-Specific CTL Clones in Melanoma Patients Is Followed by Increased Frequencies of Additional Melan-A-Specific T Cells","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"CTL*; Adoptive cell transfer; Melanoma; Avidity; Immunology; clone (Java method); Peripheral blood mononuclear cell; Biology; Tumor-infiltrating lymphocytes; Cytotoxic T cell; Metastatic melanoma; Effector; T cell; Antigen; Cancer research; Medicine; In vitro; Immune system; CD8; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001463956,0.0002067672,0.0002270646,0.0001103828,0.0001839653,0.0002937305,0.00009632748,0.000336071,0.001156472],"category_scores_gemma":[0.0003482213,0.0001086299,0.0001877804,0.00006771069,0.0001108384,0.0001240739,0.0001090241,0.0005943615,0.0003045422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001503359,"about_ca_system_score_gemma":0.00009092492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000131275,"about_ca_topic_score_gemma":0.0001506534,"domain_scores_codex":[0.9999117,0.00002220249,0.000006015803,0.00002047599,0.00001645279,0.000023213],"domain_scores_gemma":[0.9998137,0.00006260571,0.00004381028,0.00002674189,0.00001308106,0.00003997006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001959147,0.001026878,0.1058919,0.00008694779,0.00006941026,0.005026667,0.000502217,0.0005999351,0.8300828,0.0001926782,0.0006170819,0.05394443],"study_design_scores_gemma":[0.0009832068,0.02766628,0.4461253,0.00005432386,0.0004219587,0.06834894,0.0003794956,0.006587439,0.4348443,0.0004026287,0.01414462,0.00004154428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987531,0.0002125058,0.0004975999,0.00004130273,0.000005600693,0.00001768261,0.00002281023,0.0000273116,0.000422069],"genre_scores_gemma":[0.9990321,0.00008559569,0.0003050066,0.00007764835,0.00001315192,0.00001949061,0.00006836145,0.000004938508,0.0003936885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001156472,"threshold_uncertainty_score":0.003868818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008729583622025288,"score_gpt":0.2025941234951664,"score_spread":0.1938645398731411,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}