{"id":"W2164319622","doi":"10.4049/jimmunol.175.7.4797","title":"Adoptive Transfer of Tumor-Reactive Melan-A-Specific CTL Clones in Melanoma Patients Is Followed by Increased Frequencies of Additional Melan-A-Specific T Cells","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"","keywords":"CTL*; Adoptive cell transfer; Melanoma; Avidity; Immunology; clone (Java method); Peripheral blood mononuclear cell; Biology; Tumor-infiltrating lymphocytes; Cytotoxic T cell; Metastatic melanoma; Effector; T cell; Antigen; Cancer research; Medicine; In vitro; Immune system; CD8; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009682871,0.000393254,0.001104788,0.0005194058,0.0001547774,0.000008116722,0.0008649988,0.0003776686,0.005284541],"category_scores_gemma":[0.0001060689,0.0002839035,0.0003931609,0.0003565467,0.001207323,0.0003008328,0.00006369989,0.0009494477,0.0000860727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001726114,"about_ca_system_score_gemma":0.0001942202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001919044,"about_ca_topic_score_gemma":0.00001683669,"domain_scores_codex":[0.9958422,0.001481279,0.001760503,0.0002289864,0.0001778764,0.0005091675],"domain_scores_gemma":[0.9961795,0.001750396,0.001034497,0.0004539514,0.0005575561,0.00002405589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01249668,0.001085782,0.001166271,0.0000108496,0.0009839889,0.000007130094,0.004310458,0.000009783273,0.9622579,0.0002128919,0.01482972,0.002628593],"study_design_scores_gemma":[0.006548853,0.002012333,0.03187506,0.000162223,0.00009335421,0.0002303609,0.001945224,5.160031e-7,0.88546,0.00009671836,0.07130007,0.0002752444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9570049,0.04021551,0.00009329455,0.0002995046,0.0005816972,0.0003069525,0.001230108,0.00001105028,0.0002570074],"genre_scores_gemma":[0.9948558,0.004369324,0.0001415453,0.0001475997,0.00003870391,0.0000129573,0.0001525371,0.0000361264,0.0002453735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07679781,"threshold_uncertainty_score":0.9999613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008729583622025288,"score_gpt":0.2025941234951664,"score_spread":0.1938645398731411,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}