{"id":"W2164327203","doi":"10.1093/hmg/ddi455","title":"A PYY Q62P variant linked to human obesity","year":2005,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Lawrence Berkeley National Laboratory; Joint Genome Institute; U.S. Department of Energy","keywords":"Peptide YY; Biology; Endocrinology; Body mass index; Obesity; Exon; Genetics; Internal medicine; Gene; Mutant; Receptor; Neuropeptide Y receptor; Neuropeptide; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000147524,0.0002118452,0.0001887963,0.0001320013,0.0004010515,0.0001210358,0.0004785985,0.000109441,0.0002963539],"category_scores_gemma":[0.00005523852,0.0002310545,0.0001110066,0.0002454481,0.00008612224,0.00005633909,0.0002062532,0.0001597578,0.0006464333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005495449,"about_ca_system_score_gemma":0.00002779344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001055514,"about_ca_topic_score_gemma":0.00003778394,"domain_scores_codex":[0.9981831,0.0001188995,0.0003088495,0.0005568946,0.0004435715,0.0003886544],"domain_scores_gemma":[0.9989026,0.00002031522,0.00008270739,0.0006883597,0.00005990626,0.0002461218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000004054698,0.0001484892,0.0002690113,0.00000663861,0.000004042403,0.00007217922,0.0002089967,0.001586951,0.9804233,0.01602417,0.000547811,0.0007043062],"study_design_scores_gemma":[0.0005439501,0.0002295842,0.09490442,0.00002131488,0.00002524806,0.00002635339,0.000008598419,0.0006334519,0.8365054,0.003558416,0.06307767,0.000465645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985701,0.00005050458,0.004509652,0.0005211958,0.00007123165,0.0003484185,0.000005398672,0.0001219482,0.008670713],"genre_scores_gemma":[0.9918166,0.00001027255,0.003227595,0.003236614,0.0002287282,0.00001096356,0.000006419137,0.00003847451,0.001424317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.143918,"threshold_uncertainty_score":0.9422128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02995798971385972,"score_gpt":0.2874420633618557,"score_spread":0.257484073647996,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}