{"id":"W2164335068","doi":"10.1261/rna.2346806","title":"Chlorolissoclimides: New inhibitors of eukaryotic protein synthesis","year":2006,"lang":"en","type":"article","venue":"RNA","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Cancer Institute; Canadian Institutes of Health Research; National Institute of General Medical Sciences; McGill University","keywords":"Biology; Protein biosynthesis; Ribosome; In vivo; Biochemistry; Cytotoxic T cell; In vitro; EIF4E; Cell biology; Translation (biology); Messenger RNA; Gene; RNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001278533,0.0001274373,0.000296817,0.00009035149,0.00003141649,0.000009044896,0.00007563836,0.00009382033,0.0004086494],"category_scores_gemma":[0.0002868035,0.0000917301,0.0001181605,0.0002102334,0.00005398114,0.00005290368,0.00002508931,0.0001085867,0.0000588251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003592486,"about_ca_system_score_gemma":0.00008556363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000866489,"about_ca_topic_score_gemma":0.00001906801,"domain_scores_codex":[0.9991008,0.00001865128,0.0002906781,0.000207505,0.0001822633,0.0002001039],"domain_scores_gemma":[0.9994621,0.00004277068,0.0001087803,0.0002419787,0.0000647505,0.00007967577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001157515,0.00011279,0.0006902932,0.0001823563,0.00002883996,0.00001330307,0.00002260022,0.000001084405,0.9614047,0.0001801625,0.02145162,0.01579644],"study_design_scores_gemma":[0.0002033936,0.00006853061,0.006015697,0.0004231488,0.00008324158,0.00001384573,0.00001344421,0.000004659553,0.9874975,0.0002055764,0.005365808,0.0001051497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896431,0.0006642246,0.00000468772,0.004479552,0.00009632051,0.0003799052,0.000006584705,0.00005392701,0.004671692],"genre_scores_gemma":[0.991172,0.00001772334,0.001054673,0.0001000588,0.0007681025,0.000001082997,0.000004299605,0.0000189221,0.00686313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02609275,"threshold_uncertainty_score":0.4474425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01081895121370955,"score_gpt":0.220599565563951,"score_spread":0.2097806143502415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}