{"id":"W2164389688","doi":"10.1111/j.1365-2516.2008.01718.x","title":"Progress in the molecular biology of inherited bleeding disorders","year":2008,"lang":"en","type":"review","venue":"Haemophilia","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Howard Hughes Medical Institute","keywords":"Haemophilia; Medicine; Haemophilia A; Clotting factor; Genetic enhancement; Intensive care medicine; Computational biology; Gene; Biology; Surgery; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000266943,0.000358528,0.001568057,0.0004703037,0.00004996468,0.000007795345,0.0003584036,0.0004229572,0.00004490527],"category_scores_gemma":[0.0000806188,0.0001951782,0.0005145636,0.001033567,0.0004693965,0.00002220769,0.00008826971,0.0006250417,0.00003511942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007665798,"about_ca_system_score_gemma":0.0002979551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002102406,"about_ca_topic_score_gemma":0.00000426496,"domain_scores_codex":[0.9979683,0.0002904615,0.0005859896,0.0003900527,0.0003339364,0.0004312371],"domain_scores_gemma":[0.9989744,0.0001715992,0.0001673676,0.0005510088,0.00005533221,0.00008024279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001883517,0.000350187,0.001729747,0.007697356,0.0002385909,0.0004530301,0.0002018537,4.173112e-8,0.000003957939,0.0004382359,0.0003169954,0.9885511],"study_design_scores_gemma":[0.0007766448,0.0003866843,0.0002363051,0.007768319,0.0003782989,0.0003641052,0.00004395477,0.000005924963,0.000008282537,0.000235852,0.9895672,0.0002284969],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001342996,0.9943262,0.000002196569,0.0005442406,0.00007389767,0.001921419,0.00001673524,0.00002422392,0.001748079],"genre_scores_gemma":[0.002583296,0.9965034,0.0001343684,0.00003631023,0.00009995251,0.0002446203,0.0002157491,0.00004944,0.000132843],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9892501,"threshold_uncertainty_score":0.7959138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06884381670161026,"score_gpt":0.4064176084687297,"score_spread":0.3375737917671194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}