{"id":"W2164455762","doi":"10.1016/j.eururo.2008.09.037","title":"Re: Temsirolimus, Interferon Alfa, or Both for Advanced Renal-Cell Carcinoma","year":2008,"lang":"en","type":"letter","venue":"European Urology","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Temsirolimus; Medicine; Renal cell carcinoma; Interferon alfa; Oncology; Internal medicine; Interferon; Alpha interferon; Discovery and development of mTOR inhibitors; Virology; PI3K/AKT/mTOR pathway; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006017984,0.0005551465,0.0008684687,0.0003464058,0.001629126,0.0008872164,0.0006544461,0.01592048,0.006880545],"category_scores_gemma":[0.003956587,0.0002444847,0.0007317233,0.0003595189,0.0007188565,0.001163876,0.0004061266,0.009003909,0.003332018],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00200225,"about_ca_system_score_gemma":0.001301141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002380974,"about_ca_topic_score_gemma":0.006232779,"domain_scores_codex":[0.9994352,0.0001912775,0.0000550624,0.00006392493,0.0001472553,0.0001071805],"domain_scores_gemma":[0.9994417,0.0002810734,0.00005045292,0.00001761325,0.00007262173,0.0001364943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005385036,0.000143152,0.003588347,0.0001525378,0.00006159527,0.03457447,0.0001347749,0.0005036173,0.0008585316,0.005118334,0.9226192,0.031707],"study_design_scores_gemma":[0.001056938,0.0005565691,0.008854067,0.0005236423,0.0001223764,0.06284909,0.000533308,0.003207123,0.001118579,0.0138159,0.9072827,0.00007971175],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.00700333,0.005213882,0.0002939962,0.9411303,0.01668011,0.00004282556,0.0001268007,0.0000603624,0.02944836],"genre_scores_gemma":[0.07587821,0.006945225,0.0009988233,0.7567635,0.07717697,0.000126571,0.0001943155,0.00005193778,0.08186445],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.01592048,"threshold_uncertainty_score":0.02301776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03724392434054155,"score_gpt":0.2547802718044395,"score_spread":0.217536347463898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}