{"id":"W2164463174","doi":"10.1074/jbc.m404192200","title":"Spermatocyte/Spermatid-specific Thioredoxin-3, a Novel Golgi Apparatus-associated Thioredoxin, Is a Specific Marker of Aberrant Spermatogenesis","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Spermatid; Spermatocyte; Biology; Cell biology; Germ cell; Golgi apparatus; Thioredoxin; Acrosome; Spermatogenesis; Sperm; Molecular biology; Genetics; Gene; Meiosis; Endoplasmic reticulum","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009803646,0.0003397441,0.0001377421,0.0003840498,0.0001882009,0.0001883519,0.0001357602,0.0002425444,0.0005884251],"category_scores_gemma":[0.00006699232,0.0001057173,0.0002448012,0.000220932,0.0002231502,0.0001344919,0.0001671495,0.0002131384,0.0002810334],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001142624,"about_ca_system_score_gemma":0.0001753863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002623018,"about_ca_topic_score_gemma":0.000443154,"domain_scores_codex":[0.9999455,0.000006417841,0.000004601929,0.00001720062,0.00001779011,0.000008506046],"domain_scores_gemma":[0.9999005,0.000005962207,0.0000383289,0.000007203038,0.00001882288,0.00002915592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00006505325,0.000007733812,0.004827271,0.00006702806,0.00001548768,0.0003342986,0.00003598074,0.0000288522,0.9912856,0.0001372799,0.00005005547,0.003145294],"study_design_scores_gemma":[0.00004710643,0.000949181,0.2263412,0.00003451873,0.0001607928,0.01813076,0.000199979,0.001507577,0.7352202,0.0006736379,0.01670998,0.00002509441],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855264,0.005497193,0.00753878,0.00009432664,0.00005027732,0.00002159318,0.0003496062,0.0001462448,0.00077547],"genre_scores_gemma":[0.9920149,0.002030651,0.00337781,0.00005355791,0.0000303016,0.00000817915,0.0008653183,0.000009912794,0.001609453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005884251,"threshold_uncertainty_score":0.001968443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02450305232581564,"score_gpt":0.2529432849084961,"score_spread":0.2284402325826805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}