{"id":"W2164493870","doi":"10.1534/genetics.104.033266","title":"Haploidy, Diploidy and Evolution of Antifungal Drug Resistance in Saccharomyces cerevisiae","year":2004,"lang":"en","type":"article","venue":"Genetics","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Ploidy; Genetics; Saccharomyces cerevisiae; Antifungal drug; Population; Mutation; Drug resistance; Nonsynonymous substitution; Gene; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003223225,0.0002425219,0.0002521365,0.0003357911,0.0001465873,0.0002630853,0.0001481793,0.0001808809,0.0005941061],"category_scores_gemma":[0.0008688838,0.0001478935,0.0001989939,0.0002303119,0.0002649781,0.0002657956,0.0002702508,0.0003356613,0.00008702054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003507359,"about_ca_system_score_gemma":0.0001653752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008824365,"about_ca_topic_score_gemma":0.0009561991,"domain_scores_codex":[0.9998593,0.00003800753,0.00001957135,0.00004545774,0.00002377797,0.0000139032],"domain_scores_gemma":[0.9992192,0.0003746669,0.000212473,0.00005970736,0.00004398058,0.00008997865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006306769,0.00005335861,0.02225586,0.0001160458,0.00004476364,0.0001998921,0.0001603805,0.00427483,0.9631436,0.0005342478,0.00003889733,0.008547422],"study_design_scores_gemma":[0.000294127,0.004873974,0.3492258,0.00005357651,0.0002036189,0.002031437,0.0005713149,0.03485736,0.5976858,0.004387294,0.005623681,0.0001920517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982188,0.0005605082,0.0008639847,0.00002111578,0.000003659821,0.000007932369,0.0001440097,0.000007583303,0.0001723286],"genre_scores_gemma":[0.9975579,0.0003819575,0.001399045,0.00002644525,0.000002816891,0.00001170975,0.0003501264,0.000008025724,0.0002620026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008824365,"threshold_uncertainty_score":0.002544701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00398803277574596,"score_gpt":0.2212399946347227,"score_spread":0.2172519618589767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}