{"id":"W2164493870","doi":"10.1534/genetics.104.033266","title":"Haploidy, Diploidy and Evolution of Antifungal Drug Resistance in Saccharomyces cerevisiae","year":2004,"lang":"en","type":"article","venue":"Genetics","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Ploidy; Genetics; Saccharomyces cerevisiae; Antifungal drug; Population; Mutation; Drug resistance; Nonsynonymous substitution; Gene; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001374239,0.0001287731,0.0001457771,0.00006508059,0.00003789877,0.00001065524,0.0001334167,0.0001046511,0.000004738953],"category_scores_gemma":[0.00003469252,0.00013824,0.00004168471,0.0001327338,0.0001329259,0.000002683964,0.00009379986,0.00006832083,0.000002946983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003175267,"about_ca_system_score_gemma":0.00009537553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002565719,"about_ca_topic_score_gemma":0.001491894,"domain_scores_codex":[0.9990895,0.00003655611,0.0002644516,0.0002854422,0.0001256236,0.0001983781],"domain_scores_gemma":[0.9995089,0.000005710093,0.00008701968,0.0002725496,0.00006491903,0.00006085462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001158653,0.0001961486,0.1214638,0.000166702,0.00004337778,0.00000434298,0.0003268396,0.003483396,0.8672106,0.005516684,0.0007431749,0.0007290737],"study_design_scores_gemma":[0.004149643,0.0003526617,0.8033205,0.0002065883,0.00005992525,0.00002865998,0.0005602227,0.0004930699,0.1615326,0.01208843,0.01633597,0.0008717307],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838781,0.01150531,0.003574734,0.0001897933,0.00006827564,0.0001430556,0.00002151437,0.000007731991,0.0006114992],"genre_scores_gemma":[0.9893448,0.001471057,0.008602965,0.00003965277,0.00005568506,0.000005332257,0.0000267342,0.00001657792,0.0004372377],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.705678,"threshold_uncertainty_score":0.5637265,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00398803277574596,"score_gpt":0.2212399946347227,"score_spread":0.2172519618589767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}