{"id":"W2164526978","doi":"10.1128/mcb.21.5.1647-1655.2001","title":"Pir1p Mediates Translocation of the Yeast Apn1p Endonuclease into the Mitochondria To Maintain Genomic Stability","year":2001,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Mitochondrion; Mitochondrial DNA; AP site; Cytoplasm; Mutant; DNA damage; Endonuclease; Methyl methanesulfonate; DNA repair; DNA-(apurinic or apyrimidinic site) lyase; AP endonuclease; Cell nucleus; Cell biology; Molecular biology; DNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002845784,0.0001709448,0.0001789021,0.00003599264,0.0001275535,0.00001108182,0.0003011652,0.000195715,0.00006956324],"category_scores_gemma":[0.0001317087,0.0001112976,0.0001339321,0.000142552,0.0002900363,0.000002069032,0.0001463362,0.0001183997,0.00001151178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001148164,"about_ca_system_score_gemma":0.00005803879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001227753,"about_ca_topic_score_gemma":0.0002035874,"domain_scores_codex":[0.9985862,0.000425212,0.0002711564,0.0004050489,0.00007545476,0.0002368997],"domain_scores_gemma":[0.9991589,0.00001985522,0.00008052385,0.0005773389,0.00006870565,0.00009465072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000155648,0.00003634709,0.002528547,0.000007324683,0.0000323183,0.000002646987,0.0002908081,0.00002277863,0.9922722,0.0009978539,0.00008081648,0.003572712],"study_design_scores_gemma":[0.0004918065,0.0002853316,0.0006592199,0.000004709144,0.00003371799,0.00002817815,0.0002288381,0.0000323085,0.9547802,0.00117894,0.04212164,0.0001550834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9570669,0.001443172,0.03897841,0.001337573,0.0004295048,0.0004426453,0.00001850576,0.000008097411,0.0002752175],"genre_scores_gemma":[0.9978471,0.0001411666,0.0004988964,0.001121201,0.0001485604,0.00004209525,0.00008335037,0.00001797802,0.00009961476],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04204082,"threshold_uncertainty_score":0.4538583,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00720037868915958,"score_gpt":0.2142815313406528,"score_spread":0.2070811526514933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}