{"id":"W2164526978","doi":"10.1128/mcb.21.5.1647-1655.2001","title":"Pir1p Mediates Translocation of the Yeast Apn1p Endonuclease into the Mitochondria To Maintain Genomic Stability","year":2001,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Mitochondrion; Mitochondrial DNA; AP site; Cytoplasm; Mutant; DNA damage; Endonuclease; Methyl methanesulfonate; DNA repair; DNA-(apurinic or apyrimidinic site) lyase; AP endonuclease; Cell nucleus; Cell biology; Molecular biology; DNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002097771,0.0006762739,0.000332071,0.0002331812,0.0001921804,0.0003301168,0.0004673262,0.0002988498,0.001538991],"category_scores_gemma":[0.0002798786,0.0002214208,0.0002498709,0.0001332517,0.0003000368,0.0002393142,0.0006832884,0.0005871517,0.001306912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003898952,"about_ca_system_score_gemma":0.0001858425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003050998,"about_ca_topic_score_gemma":0.0002640316,"domain_scores_codex":[0.9997737,0.00002848414,0.00001502636,0.00007441684,0.00007442975,0.00003391109],"domain_scores_gemma":[0.999817,0.00002427322,0.00005486658,0.00002736826,0.00001897072,0.00005771075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007650424,0.00002101072,0.0001746751,0.00004554913,0.000002377725,0.00007315536,0.00001277567,0.00004251273,0.9982804,0.00008693473,0.00003709993,0.001146939],"study_design_scores_gemma":[0.00001592258,0.000124549,0.003515987,0.000006157968,0.000007038316,0.0004858196,0.00001986266,0.001727033,0.9916191,0.00007607227,0.002396154,0.000006140059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830183,0.001540304,0.01220786,0.0001254582,0.00005102866,0.00004956898,0.0005650236,0.0004305378,0.002011997],"genre_scores_gemma":[0.9855145,0.0006572994,0.007952948,0.00004337853,0.00001596183,0.00006433992,0.001678647,0.00008199839,0.003990869],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001538991,"threshold_uncertainty_score":0.00514847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00720037868915958,"score_gpt":0.2142815313406528,"score_spread":0.2070811526514933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}