{"id":"W2164563042","doi":"10.1158/1078-0432.ccr-05-0621","title":"Metronomic Low-Dose Chemotherapy Boosts CD95-Dependent Antiangiogenic Effect of the Thrombospondin Peptide ABT-510: A Complementation Antiangiogenic Strategy","year":2005,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Heart, Lung, and Blood Institute","keywords":"Angiogenesis; Docetaxel; Cisplatin; Cancer research; Endothelial stem cell; In vivo; Medicine; Fas receptor; Progenitor cell; Pharmacology; Apoptosis; Chemotherapy; Biology; Programmed cell death; Internal medicine; Stem cell; In vitro; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001017523,0.0002871151,0.0002212811,0.000171189,0.00008632924,0.0002001552,0.0002154375,0.0001968032,0.0008232512],"category_scores_gemma":[0.00007008471,0.0001003721,0.0001726061,0.0001179054,0.0001589216,0.0001636235,0.0001322407,0.0004864172,0.0001373738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002303569,"about_ca_system_score_gemma":0.0002168908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000289493,"about_ca_topic_score_gemma":0.0005150941,"domain_scores_codex":[0.9999194,0.00001268256,0.000007788295,0.00001692024,0.000020461,0.00002273278],"domain_scores_gemma":[0.9999635,0.000005038122,0.000009063077,0.000005969035,0.000003816555,0.00001259508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002186774,0.0001793901,0.0001325512,0.00003637249,0.000007373553,0.00004043124,0.000009875791,0.0002540574,0.9952562,0.0001609886,0.00006723343,0.003636886],"study_design_scores_gemma":[0.000155851,0.003723486,0.001646059,0.000005473512,0.00002926893,0.0003119034,0.000008481948,0.001513392,0.990383,0.00004242839,0.002174372,0.000006304601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968791,0.0005284532,0.001492715,0.00006576167,0.00001915609,0.00006305731,0.00008775973,0.00004411456,0.0008199383],"genre_scores_gemma":[0.9972016,0.0003173427,0.001619779,0.00002859764,0.000005567026,0.00002765043,0.0001422223,0.000004519253,0.0006527176],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008232512,"threshold_uncertainty_score":0.002754092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08055689484300803,"score_gpt":0.4719427441858524,"score_spread":0.3913858493428444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}