{"id":"W2164563042","doi":"10.1158/1078-0432.ccr-05-0621","title":"Metronomic Low-Dose Chemotherapy Boosts CD95-Dependent Antiangiogenic Effect of the Thrombospondin Peptide ABT-510: A Complementation Antiangiogenic Strategy","year":2005,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Heart, Lung, and Blood Institute","keywords":"Angiogenesis; Docetaxel; Cisplatin; Cancer research; Endothelial stem cell; In vivo; Medicine; Fas receptor; Progenitor cell; Pharmacology; Apoptosis; Chemotherapy; Biology; Programmed cell death; Internal medicine; Stem cell; In vitro; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002755299,0.0002573288,0.0004426972,0.0001018608,0.0002105097,0.00004464238,0.0007873843,0.0002513795,0.0007121655],"category_scores_gemma":[0.0001110409,0.0001883628,0.0007534712,0.0003641075,0.000509986,0.00001378186,0.0003066197,0.0003112571,0.00005391452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000144553,"about_ca_system_score_gemma":0.0004682738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003665129,"about_ca_topic_score_gemma":0.0007614288,"domain_scores_codex":[0.9964187,0.0008802151,0.0007549445,0.0007052925,0.0005955782,0.000645243],"domain_scores_gemma":[0.9983194,0.0002139271,0.0002423751,0.00082705,0.000231419,0.0001658255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002290144,0.0004721358,0.2102524,0.0001339203,0.00109855,0.000003045042,0.00008583377,0.0006758971,0.6958857,0.00009419742,0.02791402,0.06109422],"study_design_scores_gemma":[0.005035409,0.001847312,0.2446789,0.0001016297,0.0001272184,0.000005618402,0.00009630808,0.0002954855,0.72201,0.00003246229,0.02535874,0.0004108395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911801,0.006401345,0.00007807603,0.0006473576,0.0003386761,0.0008428631,0.0001137324,0.00001103669,0.0003868347],"genre_scores_gemma":[0.9934199,0.003439803,0.00008471887,0.0002822908,0.001457518,0.0001324196,0.00006048747,0.00005823614,0.001064557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06068338,"threshold_uncertainty_score":0.7797713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08055689484300803,"score_gpt":0.4719427441858524,"score_spread":0.3913858493428444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}