{"id":"W2164603058","doi":"10.1158/1078-0432.ccr-08-0276","title":"Combination Chemotherapy and ALVAC-CEA/B7.1 Vaccine in Patients with Metastatic Colorectal Cancer","year":2008,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":121,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sanofi (Canada); Concordia University; McGill University; Ottawa Regional Cancer Foundation","funders":"","keywords":"Medicine; Colorectal cancer; Chemotherapy; Cancer; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001289083,0.0001664331,0.0004446394,0.0002098486,0.0002837229,0.00001486691,0.000227862,0.000178808,0.001040159],"category_scores_gemma":[0.0002198592,0.0001248363,0.00005625976,0.0004307923,0.0006594092,0.0001347771,0.00007267578,0.000880326,0.00004844656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001205922,"about_ca_system_score_gemma":0.0002986118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001243033,"about_ca_topic_score_gemma":0.0003578884,"domain_scores_codex":[0.9973544,0.001104158,0.0004789285,0.0004030534,0.0001413156,0.0005181466],"domain_scores_gemma":[0.9983522,0.0009886388,0.00009975874,0.0002194901,0.0003033998,0.00003656281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01937965,0.00117561,0.9298577,0.00002460666,0.0003327846,0.000009273117,0.0005867534,0.000002930847,0.005900277,0.00004781,0.002933479,0.03974916],"study_design_scores_gemma":[0.01619257,0.001953605,0.9631937,0.00007489666,0.00001145399,0.000005658636,0.00005499842,0.000005432361,0.007794945,0.00005070753,0.01049648,0.0001655297],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885159,0.00928929,0.000006501803,0.001142974,0.000263572,0.0006580978,0.00002286242,0.00002293846,0.00007782951],"genre_scores_gemma":[0.9889576,0.009028629,0.00002355992,0.0002920019,0.00002487674,0.0002043396,0.00003398445,0.00002888749,0.001406148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03958363,"threshold_uncertainty_score":0.999873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07841285888194537,"score_gpt":0.4210567814780933,"score_spread":0.3426439225961479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}