{"id":"W2164615447","doi":"10.1158/1055-9965.epi-08-0689","title":"Two Estrogen-Related Variants in <i>CYP19A1</i> and Endometrial Cancer Risk: A Pooled Analysis in the Epidemiology of Endometrial Cancer Consortium","year":2009,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute; National Institutes of Health","keywords":"Endometrial cancer; Epidemiology; Estrogen; Oncology; Gynecology; Medicine; Epidemiology of cancer; Cancer; Internal medicine; Biology; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.007880872,0.0004097219,0.001417222,0.0008198857,0.0001007279,0.000005452675,0.000379139,0.0007898702,0.00006339979],"category_scores_gemma":[0.003646055,0.0003182974,0.0005656017,0.002016315,0.0004409811,0.00001959571,0.00008407413,0.000542741,0.000001504557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001248019,"about_ca_system_score_gemma":0.0002688362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005321885,"about_ca_topic_score_gemma":0.002061265,"domain_scores_codex":[0.9904545,0.005952837,0.001699234,0.0009738844,0.0001317593,0.000787787],"domain_scores_gemma":[0.9962776,0.001737634,0.001254212,0.0005009904,0.00008763404,0.0001419369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002536298,0.0002184688,0.9464126,0.00002047902,0.00375791,0.00001081532,0.0000895138,0.003545016,0.02089972,0.0004465619,0.0003860069,0.02167662],"study_design_scores_gemma":[0.0139147,0.001118721,0.9692292,0.0001895938,0.003549474,0.0000246593,0.00009593045,0.002173175,0.00432402,0.004310008,0.0004717352,0.0005988076],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8533137,0.1430834,0.0006504343,0.001285119,0.0005882407,0.0009084168,0.00009365474,0.00001299657,0.00006403816],"genre_scores_gemma":[0.9636695,0.03448059,0.0005372479,0.0005085645,0.0002341379,0.0003113211,0.0001931612,0.00001968497,0.00004575115],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1103558,"threshold_uncertainty_score":0.9999269,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02281046254236355,"score_gpt":0.3517728284384104,"score_spread":0.3289623658960468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}