{"id":"W2164645209","doi":"10.1007/s00216-006-0303-y","title":"The Process Analytical Technology initiative and multivariate process analysis, monitoring and control","year":2006,"lang":"en","type":"article","venue":"Analytical and Bioanalytical Chemistry","topic":"Fault Detection and Control Systems","field":"Engineering","cited_by":127,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Process analytical technology; Process (computing); Quality (philosophy); Reliability (semiconductor); Process control; Computer science; Process engineering; Process capability; Work in process; Multivariate statistics; Quality by Design; Multivariate analysis; Statistical process control; Reliability engineering; Risk analysis (engineering); Engineering; Operations management; Business","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008891188,0.001005351,0.001012589,0.001762911,0.000711307,0.002836141,0.00168437,0.001795938,0.00422349],"category_scores_gemma":[0.008522836,0.000369008,0.0006680822,0.00227712,0.001779341,0.005536535,0.003100634,0.003520691,0.001692223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001219414,"about_ca_system_score_gemma":0.006221042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001352898,"about_ca_topic_score_gemma":0.00213266,"domain_scores_codex":[0.9952765,0.00111433,0.0002212581,0.0005331327,0.002511063,0.0003437359],"domain_scores_gemma":[0.9909232,0.00215969,0.001047147,0.001036639,0.003534151,0.001299096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0005142111,0.0004718464,0.004094333,0.000525725,0.00007325827,0.000160472,0.0001919626,0.002150052,0.01521529,0.2863003,0.138221,0.5520815],"study_design_scores_gemma":[0.0001473364,0.0008753045,0.007056199,0.0002113041,0.0001103539,0.0008358161,0.0001785813,0.02786352,0.04607159,0.07135455,0.8451934,0.0001020328],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.01984098,0.0400446,0.7988718,0.0464761,0.006465667,0.0004743427,0.001616625,0.006800963,0.07940896],"genre_scores_gemma":[0.1713539,0.02097112,0.7210215,0.006129596,0.005761364,0.0009138935,0.005952748,0.001081124,0.06681474],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.008891188,"threshold_uncertainty_score":0.04702163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005649245639014489,"score_gpt":0.2409527106858245,"score_spread":0.23530346504681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}