{"id":"W2164674436","doi":"10.1200/jco.2011.37.0536","title":"Survival Benefit From Up-Front Fluorouracil, Leucovorin, and Irinotecan/Cetuximab in Metastatic Colorectal Cancer: Is It Just a Now-or-Never Result?","year":2011,"lang":"en","type":"letter","venue":"Journal of Clinical Oncology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Credit Valley Hospital","funders":"","keywords":"Medicine; Cetuximab; Irinotecan; Fluorouracil; Colorectal cancer; Oncology; Internal medicine; FOLFIRI; Oxaliplatin; Chemotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005691169,0.000912332,0.001987789,0.0006131057,0.00103877,0.002133996,0.002567955,0.008951088,0.004633618],"category_scores_gemma":[0.02529997,0.0004956588,0.001174794,0.0006810241,0.001324496,0.002590243,0.0005776816,0.0147479,0.002197163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001430298,"about_ca_system_score_gemma":0.001524702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001007082,"about_ca_topic_score_gemma":0.00187625,"domain_scores_codex":[0.9979926,0.0007900958,0.0002822877,0.0002976624,0.00044662,0.0001907226],"domain_scores_gemma":[0.9867395,0.00863394,0.001090048,0.0002054367,0.002622625,0.000708401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008218712,0.00004674994,0.0007082879,0.0009738827,0.0001366886,0.0005177158,0.00006239484,0.000108427,0.0002126552,0.0005721882,0.9699146,0.0259244],"study_design_scores_gemma":[0.001192523,0.0007918609,0.006562402,0.002673747,0.001033316,0.003068119,0.0004046494,0.001800997,0.001617562,0.005063417,0.9756006,0.0001908836],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002019981,0.02729894,0.0003110182,0.7387757,0.2297178,0.00003402582,0.0003267595,0.00007307293,0.001442624],"genre_scores_gemma":[0.01578288,0.01498036,0.0003517734,0.4454389,0.5182132,0.0000471905,0.0001268631,0.00005869038,0.005000169],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.008951088,"threshold_uncertainty_score":0.03009814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2747234193955875,"score_gpt":0.4696427834546625,"score_spread":0.1949193640590751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}