{"id":"W2164699248","doi":"10.1017/s1462399411002134","title":"Neuronal receptors as targets for the action of amyloid-beta protein (Aβ) in the brain","year":2012,"lang":"en","type":"review","venue":"Expert Reviews in Molecular Medicine","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Neurodegeneration; Receptor; Neurotoxicity; Neuroscience; Amyloid beta; Biology; Basal forebrain; Alzheimer's disease; Cholinergic; Medicine; Biochemistry; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003026475,0.0009833538,0.001225507,0.001662303,0.0002591254,0.0007064561,0.0007944366,0.001033024,0.002663448],"category_scores_gemma":[0.0002794717,0.0002689078,0.0003474347,0.002116222,0.0003703877,0.001098688,0.0004723744,0.001316132,0.003965921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004938372,"about_ca_system_score_gemma":0.0007323194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009137313,"about_ca_topic_score_gemma":0.001439795,"domain_scores_codex":[0.9998666,0.00001835531,0.00001757965,0.00002331939,0.00006135866,0.00001279685],"domain_scores_gemma":[0.9999083,0.00002655339,0.0000185256,0.000003885396,0.00003166803,0.00001108686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009143996,0.00007868678,0.0001307957,0.01405857,0.00005867884,0.0004056156,0.00008042988,0.0003719996,0.008550836,0.003488934,0.02396183,0.9487222],"study_design_scores_gemma":[0.00002046818,0.00009574868,0.0009193482,0.002351865,0.0000766493,0.002118866,0.0000600356,0.00006178446,0.001238299,0.001382085,0.9916585,0.00001623507],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001886247,0.9982098,0.0001439525,0.0001127356,0.0001436358,0.000005441587,0.00001438137,0.000007554492,0.001173811],"genre_scores_gemma":[0.0005311138,0.9982152,0.0001727016,0.00007339865,0.00007744292,0.000005414078,0.00002152985,9.495892e-7,0.0009022633],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002663448,"threshold_uncertainty_score":0.008910179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1188595340915733,"score_gpt":0.4395265129763596,"score_spread":0.3206669788847863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}