{"id":"W2164726096","doi":"10.1002/mus.20020","title":"Attenuation of free radical production and paracrystalline inclusions by creatine supplementation in a patient with a novel cytochrome <i>b</i> mutation","year":2004,"lang":"en","type":"article","venue":"Muscle & Nerve","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Institute for Biological Sciences; McMaster University Medical Centre","funders":"","keywords":"Missense mutation; Molecular biology; Paracrystalline; Cytochrome b; Biology; Biochemistry; Mutant; Mitochondrial DNA; Adenosine triphosphate; Mutation; Chemistry; Gene; Crystallography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001758653,0.0008068925,0.0007223757,0.0006723134,0.0008887754,0.0004179956,0.0004253577,0.00163291,0.001027309],"category_scores_gemma":[0.0008783809,0.0004613243,0.0003676719,0.0003824139,0.0006686883,0.0003906968,0.0003457273,0.0008631776,0.0003619887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003788383,"about_ca_system_score_gemma":0.0003073176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00132824,"about_ca_topic_score_gemma":0.001248136,"domain_scores_codex":[0.9998148,0.00001975439,0.00002895727,0.00007093575,0.00002584257,0.00003969345],"domain_scores_gemma":[0.9996189,0.0001101818,0.00008906059,0.00002486592,0.00002742507,0.0001295679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0008352155,0.0003178368,0.03040623,0.00009240674,0.00004806734,0.8946689,0.0009766576,0.0002637514,0.06511208,0.0003162657,0.0003273247,0.006635305],"study_design_scores_gemma":[0.0001532116,0.001813372,0.05318283,0.00002218263,0.00008398104,0.9271102,0.0002085027,0.001250494,0.01505206,0.0001977727,0.0008938525,0.00003159475],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984091,0.0001865302,0.0004330195,0.0002147699,0.00001709514,0.00002194946,0.00004499911,0.00003478287,0.0006378249],"genre_scores_gemma":[0.9990886,0.0001126153,0.0003098237,0.00007154852,0.00002745277,0.000005487576,0.00003603066,0.000009599094,0.00033868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00163291,"threshold_uncertainty_score":0.003436685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008206282551987073,"score_gpt":0.2324903477264988,"score_spread":0.2242840651745117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}