{"id":"W2164743709","doi":"10.1017/s1431927611007008","title":"Examining Pancreatic Islet Lipotoxicity by Two-photon NAD(P)H imaging in a Microfluidic Device","year":2011,"lang":"en","type":"article","venue":"Microscopy and Microanalysis","topic":"Microfluidic and Capillary Electrophoresis Applications","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Lipotoxicity; Islet; NAD+ kinase; Microfluidics; Materials science; Nanotechnology; Chemistry; Internal medicine; Medicine; Biochemistry; Insulin; Insulin resistance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002914782,0.0003782441,0.0004984331,0.0003225991,0.0001658486,0.00007219923,0.0002730463,0.0001040146,0.0002269569],"category_scores_gemma":[0.000009627388,0.0004072563,0.00009959965,0.0007425052,0.0001203069,0.0001557211,0.00006433295,0.0002662426,0.0000487156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001306426,"about_ca_system_score_gemma":0.00002681961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001188359,"about_ca_topic_score_gemma":0.00006990663,"domain_scores_codex":[0.9981737,0.00007014437,0.0005314666,0.000531382,0.00009281616,0.0006004564],"domain_scores_gemma":[0.9992703,0.00004558544,0.0000725547,0.0004303019,0.00003867985,0.0001425753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000148768,0.00005241196,0.01094475,0.00004868889,0.0001014422,0.000009582905,0.0008013012,7.541873e-7,0.9666975,0.00002270907,0.02022017,0.001085779],"study_design_scores_gemma":[0.0005219568,0.00001963977,0.001314861,0.00005350919,0.0002282016,0.00003420923,0.0003956404,0.0002263704,0.983887,0.00009109096,0.01277512,0.0004524339],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8309763,0.1644792,0.003183736,0.00001682994,0.00003255973,0.00020754,0.00004164417,0.000122315,0.0009398256],"genre_scores_gemma":[0.9315017,0.0672125,0.0005989533,0.0002874363,0.00002719289,0.00008333968,0.00007138866,0.00006434268,0.0001531337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1005254,"threshold_uncertainty_score":0.9998379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01141587129065118,"score_gpt":0.221877223609448,"score_spread":0.2104613523187968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}