{"id":"W2164815203","doi":"10.1097/tp.0b013e3181e2d6a1","title":"Potent Immunosuppression by a Bivalent Molecule Binding to CD200R and TGF-βR","year":2010,"lang":"en","type":"article","venue":"Transplantation","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Molecular biology; Transfection; Receptor; Transforming growth factor beta; Biology; Immunosuppression; TGF beta signaling pathway; Cell biology; Chemistry; Immunology; Transforming growth factor; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001545214,0.000485791,0.0001939119,0.0001741638,0.00009749091,0.0002471872,0.0002371579,0.0003120236,0.001563017],"category_scores_gemma":[0.00007890625,0.0001151718,0.0002388524,0.0001197035,0.000180453,0.0001450587,0.0003014944,0.000486356,0.0005019459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002540636,"about_ca_system_score_gemma":0.00009052677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001845038,"about_ca_topic_score_gemma":0.0002764782,"domain_scores_codex":[0.9998344,0.00002432532,0.00001266924,0.00003283914,0.00004818922,0.00004761296],"domain_scores_gemma":[0.9998922,0.00001833523,0.00003440481,0.00001152388,0.00000888049,0.00003446024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004682037,0.00001479675,0.00005420691,0.00001131835,0.000004012134,0.00001881214,0.000003063662,0.00003385175,0.9993597,0.00003597447,0.00001434101,0.0004031065],"study_design_scores_gemma":[0.00003505711,0.0003680662,0.001262696,0.000006037466,0.00002778872,0.0002448299,0.000009032342,0.0006196151,0.9948364,0.00001704459,0.002570523,0.000002890478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952857,0.001082617,0.002092498,0.00006544232,0.00002588402,0.00002297228,0.00007599287,0.00005870432,0.001290148],"genre_scores_gemma":[0.994134,0.0005215445,0.002945677,0.0001013154,0.00002511978,0.0000377462,0.0002715654,0.00001637483,0.001946812],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001563017,"threshold_uncertainty_score":0.005228817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0125998224189054,"score_gpt":0.2471379009499238,"score_spread":0.2345380785310184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}