{"id":"W2164837647","doi":"10.1186/bcr3688","title":"Developing a new generation of breast cancer clinical gene expression tests","year":2014,"lang":"en","type":"letter","venue":"Breast Cancer Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Canada Research Chairs; University of Toronto","funders":"","keywords":"Medicine; Oncology; Surgical oncology; Breast cancer; Internal medicine; Estrogen receptor; Adjuvant; Chemotherapy; Cancer; Gynecology; Bioinformatics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007965867,0.0005697431,0.0008022541,0.0002470063,0.0002730209,0.000069188,0.0007681958,0.001211774,0.0002720553],"category_scores_gemma":[0.00008357215,0.0004974348,0.0003057102,0.0003761757,0.0004488816,0.00001267903,0.000680353,0.00125933,0.00003003042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004343408,"about_ca_system_score_gemma":0.003193924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005610101,"about_ca_topic_score_gemma":0.0008779532,"domain_scores_codex":[0.9948601,0.0006996609,0.0008176839,0.001423274,0.001182231,0.001017055],"domain_scores_gemma":[0.9969534,0.0001218899,0.0004020849,0.001044949,0.001267786,0.00020995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003724746,0.00006671566,0.01966968,0.0002298897,0.0004554735,0.00002668645,0.00003919939,0.00002277271,0.04908676,0.00000635897,0.9040927,0.02593125],"study_design_scores_gemma":[0.00378968,0.0002391473,0.1468761,0.001829583,0.0002465385,0.0005088818,0.00002547073,0.00002583638,0.08783187,0.0001181487,0.7570167,0.001492006],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.04943611,0.01234805,0.00134056,0.9289439,0.002206985,0.001701908,0.003463971,0.00007606835,0.0004824308],"genre_scores_gemma":[0.3809775,0.04089689,0.007381479,0.3166964,0.2303577,0.004454491,0.007597983,0.001220762,0.01041675],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.6122475,"threshold_uncertainty_score":0.9997478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1678548222274714,"score_gpt":0.4464858983262081,"score_spread":0.2786310760987367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}