{"id":"W2164846084","doi":"10.1158/1078-0432.ccr-10-3083","title":"Induction of HLA-DP4–Restricted Anti-Survivin Th1 and Th2 Responses Using an Artificial Antigen-Presenting Cell","year":2011,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"National Cancer Institute","keywords":"Survivin; Biology; CD8; Cancer research; Antigen; Immunology; Cancer immunotherapy; T cell; Immunotherapy; Cytotoxic T cell; Antigen-presenting cell; Cancer; Immune system; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002315554,0.0003688216,0.0002658108,0.0001725288,0.0001196813,0.0002615005,0.0001517114,0.0003175245,0.001055901],"category_scores_gemma":[0.0001955751,0.00009580541,0.00022263,0.0001279253,0.0001776846,0.0001569816,0.0002123967,0.0005599858,0.0003129182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001912957,"about_ca_system_score_gemma":0.0001706251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009961881,"about_ca_topic_score_gemma":0.00008390373,"domain_scores_codex":[0.9998053,0.00004201433,0.00002529364,0.00005151377,0.00003950466,0.00003653149],"domain_scores_gemma":[0.9998714,0.00003432897,0.00003228244,0.0000216899,0.00001669455,0.00002359416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001150223,0.00006506708,0.0003655522,0.00004737434,0.00000531785,0.00003878148,0.0000116381,0.000110579,0.9975389,0.00004602942,0.00002183766,0.001633797],"study_design_scores_gemma":[0.00004724866,0.00153907,0.001965982,0.00000696102,0.00003178345,0.0004597465,0.00001535917,0.001474026,0.9924722,0.00003695777,0.001946437,0.000004341956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928709,0.0006975249,0.005373109,0.00004196868,0.00003022643,0.0001077528,0.0001368952,0.0000434572,0.0006983233],"genre_scores_gemma":[0.9936748,0.0003819471,0.004635585,0.00004946953,0.00001980817,0.00008582594,0.0003150401,0.000009296671,0.0008282119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001055901,"threshold_uncertainty_score":0.00353235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4470129665054379,"score_gpt":0.4904052656586406,"score_spread":0.04339229915320264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}