{"id":"W2164861161","doi":"10.1053/gast.2000.20196","title":"Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease","year":2000,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":460,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University; McGill University; University of Alberta","funders":"","keywords":"Medicine; Placebo; Gastroenterology; Internal medicine; Refractory (planetary science); Cytokine; Adverse effect; Crohn's disease; Kappa; Clinical trial; Therapeutic effect; Surgery; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001742961,0.0002587696,0.0009377518,0.0002511825,0.0002043467,0.0004470452,0.0002165922,0.0005774183,0.0008425796],"category_scores_gemma":[0.002357304,0.00008734843,0.0005033445,0.0001668561,0.0005775322,0.0003665038,0.0001312256,0.001142476,0.0002108051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000317323,"about_ca_system_score_gemma":0.0003200306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002832248,"about_ca_topic_score_gemma":0.0002236578,"domain_scores_codex":[0.9994357,0.0003133985,0.0000496316,0.00004302439,0.0000952838,0.00006286372],"domain_scores_gemma":[0.9981105,0.0009740686,0.0003187827,0.0001827906,0.0001279612,0.0002859395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4941839,0.008739738,0.03153379,0.001317407,0.0007343047,0.0008104378,0.0003652545,0.001767103,0.1440014,0.0007269288,0.0008656561,0.3149541],"study_design_scores_gemma":[0.06245997,0.6852947,0.1379139,0.0002877841,0.001345095,0.002543135,0.0003354359,0.003766587,0.0957517,0.0008242595,0.009413905,0.00006348622],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847831,0.01270535,0.0006311334,0.0002649164,0.0001250249,0.00006235518,0.0001491478,0.00003667533,0.001242299],"genre_scores_gemma":[0.9979246,0.001163461,0.0001611555,0.0001070457,0.0001138353,0.00002600618,0.0001126171,0.000004587288,0.0003867451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001742961,"threshold_uncertainty_score":0.009217739,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00481830610057323,"score_gpt":0.2351522541114528,"score_spread":0.2303339480108795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}