{"id":"W2164861161","doi":"10.1053/gast.2000.20196","title":"Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease","year":2000,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":460,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University; McGill University; University of Alberta","funders":"","keywords":"Medicine; Placebo; Gastroenterology; Internal medicine; Refractory (planetary science); Cytokine; Adverse effect; Crohn's disease; Kappa; Clinical trial; Therapeutic effect; Surgery; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009517905,0.0001475897,0.0001797631,0.00005895221,0.0000350569,0.000004806011,0.0001481585,0.00007561495,0.0004695535],"category_scores_gemma":[0.0000239914,0.0001521285,0.00007012442,0.00002691047,0.0002053387,0.000004874505,0.00009122093,0.00008917991,0.00001198625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004943923,"about_ca_system_score_gemma":0.00005425547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001421534,"about_ca_topic_score_gemma":0.0003402107,"domain_scores_codex":[0.998879,0.0001539889,0.0002762493,0.0003333361,0.000053445,0.0003039452],"domain_scores_gemma":[0.9994754,0.000006264189,0.00007310079,0.0002954267,0.00002438094,0.0001253811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1277718,0.001826231,0.6781286,0.0003458014,0.0004727815,0.00220162,0.0005266877,0.001346086,0.140652,0.0002833023,0.002542667,0.04390242],"study_design_scores_gemma":[0.003502041,0.000594046,0.9933447,0.00002549575,0.00001976949,0.000009358004,0.000009651023,0.00004056069,0.0005031485,0.0000344794,0.001835225,0.00008157218],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992934,0.00005831834,0.00001529211,0.00007449139,0.00005466782,0.0002043857,0.00002728709,0.000006730772,0.0002653901],"genre_scores_gemma":[0.9990214,0.00007691867,0.00002037315,0.0001205167,0.00005732061,0.0000172178,0.0001111568,0.00001646212,0.0005586374],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3152161,"threshold_uncertainty_score":0.6203622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00481830610057323,"score_gpt":0.2351522541114528,"score_spread":0.2303339480108795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}