{"id":"W2164864726","doi":"10.1128/aac.45.9.2420-2426.2001","title":"In Vitro and In Vivo Activities of Syn2836, Syn2869, Syn2903, and Syn2921: New Series of Triazole Antifungal Agents","year":2001,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"NAEJA-RGM Pharmaceuticals (Canada)","funders":"","keywords":"In vivo; Azole; Microbiology; Itraconazole; Candida albicans; Cryptococcus neoformans; Fluconazole; Candida parapsilosis; Biology; Amphotericin B; In vitro; Trichophyton; Triazole; Cryptococcosis; Chemistry; Antifungal; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002265276,0.0006168946,0.0004811621,0.0003462764,0.0001164689,0.000192954,0.0003060172,0.0002148502,0.001508694],"category_scores_gemma":[0.0002122022,0.0001075403,0.0002320627,0.0002080231,0.0001752713,0.0002887408,0.000152822,0.0005749144,0.000451636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001328092,"about_ca_system_score_gemma":0.0001607204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002725552,"about_ca_topic_score_gemma":0.0005929999,"domain_scores_codex":[0.9998446,0.0000454416,0.00001572318,0.00002013175,0.00004996445,0.00002421251],"domain_scores_gemma":[0.9998079,0.0000355868,0.0000531042,0.00001545016,0.00003313536,0.00005483742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00162749,0.0006185414,0.0006967722,0.0001289541,0.00003397638,0.0001468796,0.0000182452,0.0004155744,0.9866428,0.00003296167,0.0002138092,0.009423961],"study_design_scores_gemma":[0.0009368468,0.04884839,0.02512676,0.00003310635,0.0002266204,0.003593681,0.00006886045,0.002001151,0.910869,0.00009312874,0.008171939,0.00003053249],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888126,0.007182805,0.001073072,0.0001061538,0.00004408087,0.00009820423,0.000810958,0.0000680126,0.001804259],"genre_scores_gemma":[0.9863923,0.006409639,0.002123585,0.0001418837,0.0000519467,0.00009216202,0.002846402,0.00002125935,0.001920831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001508694,"threshold_uncertainty_score":0.005047023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01606245972610536,"score_gpt":0.2703995767109686,"score_spread":0.2543371169848633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}