{"id":"W2164896016","doi":"10.1158/0008-5472.can-09-2322","title":"The Human Ortholog of Granulocyte Macrophage Colony-Stimulating Factor and Interleukin-2 Fusion Protein Induces Potent <i>Ex vivo</i> Natural Killer Cell Activation and Maturation","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cytokine; Cell biology; Ex vivo; Natural killer cell; Interleukin 15; Granulocyte macrophage colony-stimulating factor; STAT5; Cancer research; Immunology; Interleukin; Signal transduction; In vivo; Cytotoxic T cell; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000120129,0.000381647,0.0002007383,0.0001499226,0.00006997865,0.000209501,0.00009894664,0.000199908,0.0005479128],"category_scores_gemma":[0.00008662495,0.00009793312,0.0002711812,0.0001277806,0.0001783641,0.0000876148,0.0001953585,0.0004082791,0.0002953984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002020017,"about_ca_system_score_gemma":0.0001695819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001859208,"about_ca_topic_score_gemma":0.0003519506,"domain_scores_codex":[0.9998473,0.00002709935,0.00001556795,0.00002924214,0.00005067467,0.00003002584],"domain_scores_gemma":[0.9999436,0.000008418171,0.00001834608,0.000009751159,0.000004333481,0.00001559291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009857555,0.00002906427,0.0001101559,0.00002648986,0.000005039351,0.00004797101,0.000006129518,0.00005204628,0.9987928,0.00004379406,0.00006474237,0.0007232567],"study_design_scores_gemma":[0.00002842137,0.0003912626,0.001988223,0.000003632014,0.00001477405,0.0005130575,0.000008445852,0.0005901066,0.9923866,0.00002497912,0.004048226,0.000002399065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913594,0.001828992,0.004285855,0.0001340961,0.00006205033,0.00008016764,0.0006326388,0.0001557552,0.001461174],"genre_scores_gemma":[0.9922773,0.0005622388,0.003625309,0.00008301174,0.00002098945,0.0000711981,0.00173717,0.00002212824,0.001600719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005479128,"threshold_uncertainty_score":0.001832962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02951017345977605,"score_gpt":0.3313873612824458,"score_spread":0.3018771878226698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}