{"id":"W2164924162","doi":"10.1158/0008-5472.can-05-1634","title":"Grg1 Acts as a Lung-Specific Oncogene in a Transgenic Mouse Model","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University of Toronto; SickKids Foundation; University Health Network; Princess Margaret Cancer Centre; Hospital for Sick Children; Sunnybrook Health Science Centre","funders":"Agence Nationale pour la Gestion des Déchets Radioactifs","keywords":"Genetically modified mouse; Biology; Transgene; Receptor tyrosine kinase; Cancer research; Gene isoform; Oncogene; Lung cancer; Transcription factor; Malignancy; Adenocarcinoma; Gene; Kinase; Cancer; Cell biology; Internal medicine; Cell cycle; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005051423,0.000952645,0.0003895942,0.001960814,0.0004519587,0.0005734647,0.0007966839,0.001379701,0.004284646],"category_scores_gemma":[0.0002740421,0.0004329341,0.0004742287,0.000452711,0.0009869876,0.0005188175,0.0004278496,0.002101719,0.001423347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007724657,"about_ca_system_score_gemma":0.0003481469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007026212,"about_ca_topic_score_gemma":0.001257957,"domain_scores_codex":[0.9995642,0.00009357816,0.00002741944,0.0001404499,0.0001099581,0.00006438228],"domain_scores_gemma":[0.9996665,0.00006572761,0.00009405013,0.00005878215,0.00001920196,0.00009579998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003625056,0.0003790917,0.0006311823,0.00007087993,0.00002022837,0.0009132486,0.00005743783,0.0002876713,0.9908047,0.001931029,0.0007597743,0.003782333],"study_design_scores_gemma":[0.0004200667,0.002192547,0.005517157,0.00006593265,0.00009617546,0.005997076,0.00008749888,0.004719785,0.9568868,0.0009119298,0.02307307,0.00003197243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9745711,0.002171083,0.01017423,0.002256791,0.000226681,0.0002959135,0.002221672,0.001527835,0.00655463],"genre_scores_gemma":[0.9678819,0.002097967,0.009337923,0.0005029507,0.00007121713,0.0004039118,0.002196969,0.0002137711,0.01729339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004284646,"threshold_uncertainty_score":0.01433361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05601590926126573,"score_gpt":0.3800563557760858,"score_spread":0.32404044651482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}