{"id":"W2164924162","doi":"10.1158/0008-5472.can-05-1634","title":"Grg1 Acts as a Lung-Specific Oncogene in a Transgenic Mouse Model","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University of Toronto; SickKids Foundation; University Health Network; Princess Margaret Cancer Centre; Hospital for Sick Children; Sunnybrook Health Science Centre","funders":"Agence Nationale pour la Gestion des Déchets Radioactifs","keywords":"Genetically modified mouse; Biology; Transgene; Receptor tyrosine kinase; Cancer research; Gene isoform; Oncogene; Lung cancer; Transcription factor; Malignancy; Adenocarcinoma; Gene; Kinase; Cancer; Cell biology; Internal medicine; Cell cycle; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000385131,0.0001095642,0.0001045517,0.0001081522,0.00008793512,0.00002859998,0.000198559,0.0001450924,0.00004743824],"category_scores_gemma":[0.00001389112,0.000104271,0.00006006939,0.0002349602,0.0001157799,0.000003058067,0.00007034914,0.0002078011,0.00002103611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008355163,"about_ca_system_score_gemma":0.0002791723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003880329,"about_ca_topic_score_gemma":0.0005512142,"domain_scores_codex":[0.9985346,0.0000705154,0.0001669233,0.0005188294,0.0002845372,0.0004245956],"domain_scores_gemma":[0.9993896,0.00000447203,0.00002141015,0.000352752,0.0001584327,0.00007330431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002075181,0.00008590094,0.0002678671,0.00001707526,0.00001014857,0.000002037669,0.0000433921,0.006334683,0.9875725,0.0002522018,0.004294958,0.0009117372],"study_design_scores_gemma":[0.0004828475,0.0001525826,0.0004567544,0.00001072403,0.000002715465,0.00000234781,0.00003242175,0.0004499465,0.9479567,0.0003374171,0.04997019,0.0001453261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902346,0.005839851,0.0004513162,0.0004171097,0.00005772441,0.0002865588,0.00001615702,0.000007831229,0.002688824],"genre_scores_gemma":[0.979123,0.004885741,0.0001302598,0.00003184545,0.000500842,0.0001238009,0.00003746179,0.00003171568,0.01513536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04567523,"threshold_uncertainty_score":0.4252046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05601590926126573,"score_gpt":0.3800563557760858,"score_spread":0.32404044651482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}