{"id":"W2164936738","doi":"10.1074/mcp.m111.011700","title":"Peripheral Blood Monocyte-expressed ANXA2 Gene is Involved in Pathogenesis of Osteoporosis in Humans","year":2011,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Fogarty International Center; National Institute on Aging; National Institute on Deafness and Other Communication Disorders; Canadian Institutes of Health Research","keywords":"Osteoporosis; Osteoclast; Bone resorption; In vivo; Pathogenesis; Osteoprotegerin; Bone remodeling; Monocyte; Bone density; Bone mineral; Proteomics; Biology; Immunology; Internal medicine; Medicine; Endocrinology; In vitro; Gene; Genetics; Activator (genetics)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002075545,0.0002196051,0.0001931992,0.0004239908,0.0002419752,0.0002308602,0.0001087255,0.000234916,0.001219029],"category_scores_gemma":[0.000377215,0.0001075222,0.0001580142,0.000471932,0.0001547451,0.00005836574,0.0001313124,0.0002127199,0.0001848764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008084181,"about_ca_system_score_gemma":0.0000969446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007211019,"about_ca_topic_score_gemma":0.0006515504,"domain_scores_codex":[0.9998314,0.00004591788,0.00001362606,0.00005146302,0.00004309149,0.00001442764],"domain_scores_gemma":[0.9998592,0.00002469699,0.00005638842,0.00001534056,0.00002412201,0.00002024156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002604507,0.0001875079,0.6350053,0.0002188307,0.00033944,0.001590774,0.0002385118,0.0001317073,0.3388289,0.0004044818,0.0004847643,0.01996524],"study_design_scores_gemma":[0.00002444247,0.000237863,0.9858155,0.00001716482,0.00009748525,0.001750919,0.00008532074,0.0002987424,0.009703827,0.0001632113,0.001799761,0.000005758383],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956085,0.002377491,0.001017169,0.00007296777,0.00001509734,0.000008912417,0.0003278517,0.00001286624,0.0005590791],"genre_scores_gemma":[0.9973854,0.0006104431,0.0009313456,0.00004488627,0.00001765212,0.00001403178,0.0002596551,0.000002541649,0.0007340871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001219029,"threshold_uncertainty_score":0.00407809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01599022702866348,"score_gpt":0.2112978704548724,"score_spread":0.1953076434262089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}