{"id":"W2164936738","doi":"10.1074/mcp.m111.011700","title":"Peripheral Blood Monocyte-expressed ANXA2 Gene is Involved in Pathogenesis of Osteoporosis in Humans","year":2011,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Fogarty International Center; National Institute on Aging; National Institute on Deafness and Other Communication Disorders; Canadian Institutes of Health Research","keywords":"Osteoporosis; Osteoclast; Bone resorption; In vivo; Pathogenesis; Osteoprotegerin; Bone remodeling; Monocyte; Bone density; Bone mineral; Proteomics; Biology; Immunology; Internal medicine; Medicine; Endocrinology; In vitro; Gene; Genetics; Activator (genetics)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003162635,0.0003548715,0.0004047827,0.0001755404,0.00004378464,0.00001970423,0.0004599561,0.000378751,0.00006028252],"category_scores_gemma":[0.00003670521,0.0003901191,0.0002348263,0.000274915,0.0001174613,0.00001090856,0.0002275293,0.0001841335,0.000003159245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003047462,"about_ca_system_score_gemma":0.0001059535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000445242,"about_ca_topic_score_gemma":0.0001614579,"domain_scores_codex":[0.9978353,0.00015895,0.000603987,0.0007058291,0.0002067454,0.0004891711],"domain_scores_gemma":[0.9987899,0.000003139538,0.0002007152,0.0008066663,0.0000935139,0.0001060483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001564292,0.0004773191,0.02028884,0.00005956336,0.00005305188,0.0001356333,0.0007074919,0.00006211433,0.9777266,0.00004229132,0.000007554742,0.000283089],"study_design_scores_gemma":[0.001733615,0.0003781722,0.004029649,0.00004328954,0.0000342391,0.000003593808,0.0001901233,0.0001964472,0.99257,0.0002392338,0.0001552385,0.0004263706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948923,0.001591091,0.00218646,0.00002298219,0.0000489453,0.0009004167,0.00006054927,0.00001326803,0.0002839967],"genre_scores_gemma":[0.9852574,0.0002102536,0.01380098,0.0001771394,0.00004338381,0.0002133012,0.0001296474,0.00008037833,0.00008747749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01625919,"threshold_uncertainty_score":0.999855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01599022702866348,"score_gpt":0.2112978704548724,"score_spread":0.1953076434262089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}