{"id":"W2164949714","doi":"10.1086/599790","title":"Randomized, Double‐Blind Controlled Phase 3 Trial Comparing the Immunogenicity of High‐Dose and Standard‐Dose Influenza Vaccine in Adults 65 Years of Age and Older","year":2009,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":387,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Immunogenicity; Medicine; Influenza vaccine; Live attenuated influenza vaccine; Double blind; Randomized controlled trial; Trivalent influenza vaccine; Vaccination; Virology; Inactivated vaccine; Immunology; Internal medicine; Antibody; Placebo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00236894,0.0001900419,0.001691009,0.0003009692,0.0001085722,0.00002689072,0.0001395389,0.00005237269,0.00001926297],"category_scores_gemma":[0.00207092,0.00009922855,0.0002662413,0.0002520944,0.0003860599,0.0001387336,0.0000791611,0.0003801746,3.045073e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005721283,"about_ca_system_score_gemma":0.0001728389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000359487,"about_ca_topic_score_gemma":0.00005994846,"domain_scores_codex":[0.9973931,0.0005609014,0.001149997,0.0001100242,0.0005555435,0.0002304586],"domain_scores_gemma":[0.996847,0.001533662,0.0008035808,0.0002415552,0.0004468954,0.0001272843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9885412,0.0008918152,0.004770482,0.00009365153,0.0009576959,0.00005345094,0.001549141,0.0001469592,0.0006235133,0.00005539565,0.0000506737,0.002266043],"study_design_scores_gemma":[0.9091617,0.002567541,0.08556622,0.0004639128,0.00115071,0.00005427374,0.000248725,0.00007085124,0.0002626099,0.0003584345,0.00001481701,0.00008017493],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.980452,0.01697953,0.000009998866,0.0001955979,0.00006910768,0.002190035,0.00001853424,0.000008213509,0.00007695074],"genre_scores_gemma":[0.9961804,0.003486376,0.000008628702,0.0001617304,0.0001302733,0.00001547668,9.832579e-7,0.00001107317,0.000005097675],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08079574,"threshold_uncertainty_score":0.4046423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03659778605619055,"score_gpt":0.3703904642783047,"score_spread":0.3337926782221141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}