{"id":"W2164971734","doi":"10.1158/1055-9965.epi-06-0378","title":"Reproducibility and Expression of Skin Biomarkers in Sun-Damaged Skin and Actinic Keratoses","year":2006,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute","keywords":"Spermidine; Putrescine; Actinic keratosis; Polyamine; Lesion; Proliferating cell nuclear antigen; Skin cancer; Medicine; Dermatology; Pathology; Chemistry; Cancer; Basal cell; Immunohistochemistry; Internal medicine; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001893527,0.0003095728,0.0003725137,0.0006218126,0.0001834045,0.0005191997,0.0002480311,0.0003877804,0.0009315507],"category_scores_gemma":[0.004177524,0.0001906284,0.000235484,0.0004094439,0.000449288,0.0002764925,0.0003435824,0.0002229835,0.000291023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001525557,"about_ca_system_score_gemma":0.00008118133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004196187,"about_ca_topic_score_gemma":0.0004551443,"domain_scores_codex":[0.9979761,0.0007126688,0.0001756961,0.0005545434,0.0004851666,0.00009586263],"domain_scores_gemma":[0.9975224,0.0008154081,0.0007113509,0.0003507456,0.0004945325,0.0001055023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005536431,0.0001334126,0.8637938,0.0002043501,0.0003855492,0.000169335,0.0003500575,0.0002636728,0.1090856,0.00004376149,0.00005528031,0.0199786],"study_design_scores_gemma":[0.00002059407,0.0009519962,0.9791054,0.00001113055,0.00009765957,0.0004902733,0.0001236987,0.0002564139,0.01862974,0.00003196634,0.000275521,0.000005463047],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974939,0.0009155205,0.0008697063,0.000006808919,0.000007487427,0.00002282172,0.00008737545,0.00001559967,0.0005807862],"genre_scores_gemma":[0.9991158,0.0001085189,0.000401766,0.000009373768,0.000005791242,0.00002200059,0.000120943,0.000004699893,0.0002110463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001893527,"threshold_uncertainty_score":0.010014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02313806879871462,"score_gpt":0.3343218596810466,"score_spread":0.311183790882332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}