{"id":"W2164971734","doi":"10.1158/1055-9965.epi-06-0378","title":"Reproducibility and Expression of Skin Biomarkers in Sun-Damaged Skin and Actinic Keratoses","year":2006,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute","keywords":"Spermidine; Putrescine; Actinic keratosis; Polyamine; Lesion; Proliferating cell nuclear antigen; Skin cancer; Medicine; Dermatology; Pathology; Chemistry; Cancer; Basal cell; Immunohistochemistry; Internal medicine; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002416794,0.0001797846,0.0003524096,0.00009649989,0.00006438603,0.000004582318,0.0001070984,0.0002291502,0.00001919261],"category_scores_gemma":[0.0005179716,0.0001630183,0.0001002407,0.0001544464,0.0003579494,0.0000130623,0.0001253753,0.00008272252,6.146208e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001958219,"about_ca_system_score_gemma":0.00006289719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009196789,"about_ca_topic_score_gemma":0.0005961309,"domain_scores_codex":[0.9974566,0.0006481521,0.0005806519,0.00101306,0.00004763378,0.0002539333],"domain_scores_gemma":[0.9987727,0.0001295238,0.0003156283,0.0006765747,0.00004561883,0.00005994651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002140481,0.00009251338,0.46626,0.00004355545,0.0000686261,2.722293e-7,0.00001459732,0.000009604422,0.5137399,0.00006816238,0.002124624,0.01736417],"study_design_scores_gemma":[0.0007226416,0.00006832361,0.8117427,0.0000522106,0.0000367763,0.000004828125,0.00003533252,0.00003953832,0.1826308,0.00260627,0.001909867,0.0001507109],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9757791,0.02251524,0.0007196551,0.0003697587,0.00007639763,0.0003783716,0.0000280776,0.00000830723,0.0001251045],"genre_scores_gemma":[0.9954382,0.00201827,0.00188426,0.00005075292,0.0001107573,0.0001370081,0.0001824191,0.00001358248,0.0001647582],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3454827,"threshold_uncertainty_score":0.6647695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02313806879871462,"score_gpt":0.3343218596810466,"score_spread":0.311183790882332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}