{"id":"W2165051052","doi":"10.1002/jlcr.3239","title":"Radiosynthesis of [<sup>18</sup>F]ATPFU: a potential PET ligand for mTOR","year":2014,"lang":"en","type":"article","venue":"Journal of Labelled Compounds and Radiopharmaceuticals","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Columbia College","funders":"National Institute of Mental Health","keywords":"Radiosynthesis; Chemistry; Ligand (biochemistry); Radiochemistry; Pet imaging; Positron emission tomography; Nuclear medicine; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001067684,0.000235304,0.0005938659,0.0001105077,0.0001230026,0.00004396444,0.0003204086,0.0001391482,0.00003313979],"category_scores_gemma":[0.0002464452,0.0001932447,0.0003106033,0.00008795036,0.0002156321,0.00001205523,0.0000715185,0.0001907731,0.000001040985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002521118,"about_ca_system_score_gemma":0.0001175191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000183054,"about_ca_topic_score_gemma":2.507475e-7,"domain_scores_codex":[0.9982532,0.0001589529,0.0007101171,0.0002619086,0.0002873939,0.0003284747],"domain_scores_gemma":[0.9985259,0.0002177251,0.0004313619,0.000228825,0.0003306328,0.0002656253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001379551,0.0003761089,0.0002675897,0.0001583956,0.0005523456,0.0000139229,0.00006203098,0.0004376044,0.986944,0.0001210049,0.006707564,0.00297992],"study_design_scores_gemma":[0.01466058,0.002147744,0.0001030358,0.0001837513,0.0006803689,0.0009892749,0.00007335476,0.01267639,0.7789,0.000588966,0.1885128,0.0004836913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853513,0.00677482,0.00627534,0.0006463113,0.0003946266,0.000232031,0.00003919312,0.000006681011,0.0002797041],"genre_scores_gemma":[0.991869,0.001423828,0.004890586,0.0003517496,0.001229354,0.000007741105,0.000005575214,0.00003891294,0.0001832416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.208044,"threshold_uncertainty_score":0.7880292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01869977745020575,"score_gpt":0.3027258622779535,"score_spread":0.2840260848277477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}