{"id":"W2165101502","doi":"10.1074/jbc.275.3.1959","title":"Phosphorylation of Caldesmon by p21-activated Kinase","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Queen's University","funders":"Medical Research Council; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Caldesmon; Tropomyosin; Calmodulin; Phosphorylation; Actin; Myosin; Myosin light-chain kinase; Calmodulin-binding proteins; Chemistry; Molecular biology; Biochemistry; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019129,0.0001103843,0.0001854703,0.00001072185,0.00002855606,0.00000735947,0.0001316229,0.0002340882,0.0007461834],"category_scores_gemma":[0.00009546462,0.00008369607,0.0001387723,0.00007414473,0.00008784995,0.000004479905,0.00001835555,0.0001231523,0.000001897942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001466227,"about_ca_system_score_gemma":0.00003829629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002119031,"about_ca_topic_score_gemma":4.808961e-8,"domain_scores_codex":[0.999204,0.00003646106,0.0003795207,0.0001324453,0.0001239707,0.0001236066],"domain_scores_gemma":[0.9993788,0.00001189777,0.0002704541,0.0001190368,0.0001287172,0.00009107684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002496445,0.00009706004,0.0004823833,0.00001306496,0.00002776953,0.000005040721,0.000003902071,0.000062017,0.9924001,0.000003884443,0.0008336335,0.005821511],"study_design_scores_gemma":[0.0004748047,0.0001965617,0.0004722988,0.00002613203,0.000009107019,0.00003725525,0.00001785429,0.00001213686,0.9732,0.00005393212,0.0254019,0.00009799042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960564,0.001748423,0.0002350119,0.0000652435,0.00001944895,0.00004330409,0.00001503828,0.000004319253,0.001812757],"genre_scores_gemma":[0.9987733,0.0003210181,0.0003652956,0.00006324015,0.0001315215,0.000001417951,0.00006465695,0.000006642962,0.0002728664],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02456827,"threshold_uncertainty_score":0.8170184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01206194767638868,"score_gpt":0.2394891589909075,"score_spread":0.2274272113145188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}