{"id":"W2165158368","doi":"10.1016/s0168-1702(03)00045-5","title":"Selective reovirus killing of bladder cancer in a co-culture spheroid model","year":2003,"lang":"en","type":"article","venue":"Virus Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; University of Alberta","funders":"National Cancer Institute; Alberta Heritage Foundation for Medical Research","keywords":"Biology; Cell culture; Apoptosis; In vitro; Oncolytic virus; MTT assay; Lysis; Molecular biology; In vivo; Cytotoxicity; Cancer cell; Staining; Spheroid; Cancer research; Virology; Cell biology; Virus; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003389993,0.0003693256,0.0008205715,0.0003943088,0.000404837,0.0004722528,0.0005270309,0.0005198677,0.0009409735],"category_scores_gemma":[0.0001840959,0.0002237837,0.000431637,0.000330513,0.0003184279,0.0004855075,0.00036442,0.0008255793,0.0002892069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007467634,"about_ca_system_score_gemma":0.0005855907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007821112,"about_ca_topic_score_gemma":0.006634419,"domain_scores_codex":[0.9997314,0.00005362184,0.00002142663,0.00007117628,0.00006692472,0.00005537228],"domain_scores_gemma":[0.9997359,0.00008128414,0.00004654411,0.00006847318,0.0000213617,0.00004641529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002127451,0.0000616543,0.0001319757,0.00006858625,0.00001002873,0.0001130257,0.0001020959,0.000427699,0.9969636,0.0005832409,0.0001641921,0.001161242],"study_design_scores_gemma":[0.00002582141,0.0002302517,0.0009780767,0.00000638393,0.00001617369,0.0002152212,0.00004204708,0.002913295,0.9934684,0.00006180078,0.002036897,0.000005572514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98432,0.003090127,0.008232834,0.0002231583,0.0001135138,0.0001000915,0.0006835033,0.0001811334,0.003055714],"genre_scores_gemma":[0.990203,0.0009998896,0.004308842,0.00002725955,0.00001182367,0.00006211109,0.0004063841,0.00005724747,0.003923394],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007821112,"threshold_uncertainty_score":0.01555115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05497895520337609,"score_gpt":0.4093901358129892,"score_spread":0.3544111806096131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}