{"id":"W2165249764","doi":"10.1139/o05-048","title":"MeCP2: the chromatin connection and beyond","year":2005,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"MECP2; Chromatin; Rett syndrome; DNA methylation; Biology; CpG site; Methylation; Psychological repression; Transcription (linguistics); Computational biology; Genetics; DNA; Neuroscience; Gene; Gene expression; Philosophy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001147748,0.0003468432,0.0004022015,0.00002179429,0.0001496916,0.00002761289,0.0001855887,0.0005446515,0.00002407593],"category_scores_gemma":[0.0000233911,0.0002434422,0.0001127979,0.00005668171,0.0002481221,0.000001021834,0.0002434512,0.0001722417,0.0000069008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008291319,"about_ca_system_score_gemma":0.00009065922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002673046,"about_ca_topic_score_gemma":0.000003143216,"domain_scores_codex":[0.9987838,0.00007753336,0.0002785519,0.0005805712,0.00004232874,0.0002371744],"domain_scores_gemma":[0.9994279,0.00002794741,0.0001561726,0.0002894665,0.00001902064,0.0000795372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007301896,0.00003156243,0.00000409199,0.001234599,0.00006884235,8.71876e-7,0.0000110325,9.717251e-8,0.08374608,0.0000265514,0.001171543,0.9136974],"study_design_scores_gemma":[0.0001661695,0.00009424061,0.000006155909,0.00007914355,0.0001109027,0.00007359833,0.00003599716,0.000001157441,0.01285115,0.00002472041,0.9862569,0.0002998729],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004852191,0.9905484,0.000009987332,0.00005335928,0.0001102137,0.0002367832,0.00005885279,0.000008285562,0.004121928],"genre_scores_gemma":[0.008598642,0.9891589,0.00008785769,0.0001933481,0.0001379885,0.00005566801,0.0006012573,0.00002757322,0.001138762],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9850854,"threshold_uncertainty_score":0.9927285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01187458940200965,"score_gpt":0.2545897622824901,"score_spread":0.2427151728804804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}