{"id":"W2165274292","doi":"10.1101/gad.1804409","title":"A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis","year":2009,"lang":"en","type":"article","venue":"Genes & Development","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; Scottish Funding Council; Wellcome Trust","keywords":"Ribosome biogenesis; Biology; Nutrient sensing; Cell biology; TOR signaling; Regulon; Ribosomal protein; Transcription factor; Biogenesis; Ribosome; Signal transduction; Genetics; Gene; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001926196,0.0008699769,0.0004174895,0.0004624226,0.0003684114,0.0004354863,0.0004410139,0.0005587419,0.001541988],"category_scores_gemma":[0.0001919357,0.0003427246,0.0004351754,0.000378021,0.0003895697,0.0003258432,0.0007464091,0.0004669798,0.001719364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005127889,"about_ca_system_score_gemma":0.0002753521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005300233,"about_ca_topic_score_gemma":0.0007376373,"domain_scores_codex":[0.9997854,0.00003698644,0.00002321304,0.00003546823,0.00008555139,0.00003338363],"domain_scores_gemma":[0.999843,0.00002109476,0.00004620368,0.00003367591,0.00001629376,0.00003958989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001681873,0.00002871977,0.0003111112,0.00004545942,0.000006448845,0.0002318905,0.000009315341,0.000228952,0.9939712,0.0006762932,0.0001034722,0.004219074],"study_design_scores_gemma":[0.0000300011,0.0001767389,0.002712674,0.000007419747,0.00002560256,0.001436637,0.00001676318,0.003150609,0.9813558,0.0002383786,0.01083291,0.00001644534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9705137,0.002260986,0.01981065,0.0003224994,0.00008913103,0.00009725926,0.00122974,0.001319773,0.00435631],"genre_scores_gemma":[0.9678507,0.001214484,0.0186923,0.00009358765,0.00002345207,0.0000515992,0.002248142,0.0001613519,0.009664421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001541988,"threshold_uncertainty_score":0.005158484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006089434498942121,"score_gpt":0.1848393764226777,"score_spread":0.1787499419237356,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}